Radioguided Surgery

Current Applications and Innovative Directions in Clinical Practice

  • Ken Herrmann
  • Omgo E. Nieweg
  • Stephen P. Povoski

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Introduction

  3. Detailed Methodology Part

    1. Front Matter
      Pages 13-13
    2. Thomas Wendler, Uta Eberlein, Michael Lassmann
      Pages 15-33
    3. Paulo Waelkens, Matthias N. van Oosterom, Nynke S. van den Berg, Nassir Navab, Fijs W. B. van Leeuwen
      Pages 57-73
    4. Anton Bunschoten, Nynke S. van den Berg, Renato A. Valdés Olmos, Jacobus A. K. Blokland, Fijs W. B. van Leeuwen
      Pages 75-101
    5. Michael Lassmann, Uta Eberlein
      Pages 103-111
  4. Clinical Application: Breast

    1. Front Matter
      Pages 113-113
    2. Andrea V. Barrio, Hiram S. Cody III
      Pages 115-123
    3. Richard J. Gray, Charles E. Cox, Emilia L. Dauway
      Pages 125-137
    4. Bas Pouw, Marie-Jeanne T. F. D. Vrancken Peeters, Renato A. Valdés Olmos
      Pages 139-148
  5. Clinical Application: Skin

    1. Front Matter
      Pages 149-149
    2. Omgo E. Nieweg, Roger F. Uren, John F. Thompson
      Pages 151-163
  6. Clinical Application: Head and Neck

    1. Front Matter
      Pages 165-165
    2. Remco de Bree, Christina Bluemel
      Pages 167-179
  7. Clinical Application: Thyroid and Parathyroid

    1. Front Matter
      Pages 181-181
    2. Isabella Merante Boschin, Domenico Rubello, Christina Bluemel, Ken Herrmann, Maria Rosa Pelizzo
      Pages 183-196
    3. Irene Lou, Rebecca S. Sippel, Herbert Chen
      Pages 197-207
    4. Christina Bluemel, Ken Herrmann, Gerhard Wolf, Giorgo Castagnola, Carlo Bellotti
      Pages 209-224
  8. Clinical Application: Urogenital Tract

    1. Front Matter
      Pages 225-225
    2. Henk G. van der Poel, Joost A. P. Leijte, Simon Horenblas
      Pages 227-247
  9. Clinical Application: Gastrointestinal Tract

    1. Front Matter
      Pages 265-265
    2. Dawid Murawa, Piotr Nowaczyk, Armin Wiegering
      Pages 279-297
    3. Nathan C. Hall, Christina Bluemel, Sergi Vidal-Sicart, Stephen P. Povoski
      Pages 299-311
  10. Clinical Application: Thoracic

    1. Front Matter
      Pages 313-313
    2. Leili Zarifmahmoudi, David N. Krag, Ramin Sadeghi, Reza Bagheri, Susan Shafiee
      Pages 315-333
    3. Amelia W. Maiga, Eric L. Grogan
      Pages 335-350
  11. Miscellaneous

    1. Front Matter
      Pages 351-351
    2. Erik M. Von Meyenfeldt, Karel W. E. Hulsewé
      Pages 353-358
    3. Sergi Vidal-Sicart, Ramon Rull, Clemente Barriuso, Omgo E. Nieweg
      Pages 359-369
    4. Stephen P. Povoski, Douglas A. Murrey Jr., Nathan C. Hall
      Pages 419-445
  12. Outlook: New Techniques, Image Fusion, Optical Imaging

    1. Front Matter
      Pages 447-447
    2. Dawid Murawa, Karol Połom
      Pages 449-462
    3. B. Anninga, M. Ahmed, Michael Douek
      Pages 463-470
    4. Martin Freesmeyer, Thomas Winkens
      Pages 471-480
  13. Examples (Conventional Techniques and Innovations)

    1. Front Matter
      Pages 481-481
    2. Christina Bluemel, Francisco Campos, Angela Collarino, Andreas Cramer, Stephan Dik, Alessandro Giordano et al.
      Pages 483-494
  14. Back Matter
    Pages 495-503

About this book


This book offers a comprehensive overview of the state of the art in the practice of radioguided surgery. The opening section is devoted to the basic physics principles for detection and imaging, radiation detection device technology, principles of surgical navigation, radionuclides and radiopharmaceuticals, and radiation safety. A series of chapters then address the clinical application of radioguided surgery for a variety of malignancies, including breast cancer, melanoma and other cutaneous malignancies, gynecologic malignancies, head and neck malignancies, thyroid cancer, urologic malignancies, colon cancer, gastroesophageal cancer, lung cancer, bone tumors, parathyroid adenomas, and neuroendocrine tumors. For each application, the recommended methodological approaches are discussed and the available cumulative clinical experiences of investigators from across the globe are reviewed. A conscious effort is made to highlight recent developments and innovative multidisciplinary approaches within each clinical area. Interesting issues and novel approaches are further explored through a collection of selected case reports at the end of the book. The contributing authors are all experts in their own fields, ensuring that the book will hold wide appeal for surgeons, surgical technologists, nuclear medicine physicians, nuclear medicine technologists, and various trainees.


Radioguided Surgery Gamma Probe PET Probe Gamma Camera Scintigraphy Lymphoscintigraphy PET PET/CT SPECT SPECT/CT Radioguided Occult Lesion Localization (ROLL) Sentinel Lymph Node Technetium-99m (99m-Tc) Fluorine-18 fluorodeoxyglucose (18F-FDG) Radionuclides Radiopharmaceuticals

Editors and affiliations

  • Ken Herrmann
    • 1
  • Omgo E. Nieweg
    • 2
  • Stephen P. Povoski
    • 3
  1. 1.Universitätsklinikum WürzburgDepartment of Nuclear MedicineWürzburgGermany
  2. 2.The University of SydneyMelanoma Institute AustraliaNorth SydneyAustralia
  3. 3.Arthur G. James Canc Hosp Richard J. SolThe Ohio State Univ Comp Canc CTRColumbusUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-26049-5
  • Online ISBN 978-3-319-26051-8
  • Buy this book on publisher's site