Hypertension and the Brain as an End-Organ Target

  • Hélène Girouard

Table of contents

  1. Front Matter
    Pages i-xix
  2. Laurence Desjardins-Crépeau, Louis Bherer
    Pages 21-38
  3. J. David Spence, Robert Hammond
    Pages 39-54
  4. Kenneth S. Dyson, Richard D. Hoge
    Pages 55-69
  5. Dima Obari, Sefika Ozturk Ozcelik, Hélène Girouard, Edith Hamel
    Pages 71-97
  6. Jean-Marc Chillon, Eric Thorin
    Pages 135-153
  7. T. Michael De Silva, Ricardo A. Peña Silva, Frank M. Faraci
    Pages 155-180
  8. Vermalí Rodríguez, Annette D. de Kloet, Colin Sumners
    Pages 181-194
  9. Tracey A. Van Kempen, Jose Marques-Lopes, Michael J. Glass, Teresa A. Milner
    Pages 195-221

About this book


The first comprehensive overview of the effects of hypertension on the brain. The book discusses not only the relationship between hypertension and stroke, but also the much less studied relationship between hypertension and cognitive decline and neurodegenerative diseases such as Alzheimer's. It seeks to answer two important questions. First, what are the conditions under which hypertension is associated with stroke, cognitive decline, and neurodegenerative disease? And second, what are the biological mechanisms by which hypertension alters brain homeostasis? By looking at the biological mechanisms of these relationships, this book provides insight to neuroscientists and neurologists regarding why anti-hypertension treatments make a big difference in the case of stroke, but have very little impact on cognitive decline and brain aging.


aging brain imaging cerebrovascular dementia hypertension

Editors and affiliations

  • Hélène Girouard
    • 1
  1. 1.Faculty of MedicineUniversité de MontréalMontréalCanada

Bibliographic information