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Post-transcriptional Mechanisms in Endocrine Regulation

  • K.M.J. Menon, PhD
  • Aaron Goldstrohm, PhD

Table of contents

  1. Front Matter
    Pages i-xiv
  2. René Arvola, Elizabeth Abshire, Jennifer Bohn, Aaron C. Goldstrohm
    Pages 1-36
  3. Irina Vlasova-St. Louis, Paul R. Bohjanen
    Pages 55-70
  4. K. M. J. Menon, Bindu Menon, Thippeswamy Gulappa
    Pages 71-89
  5. Pavla Brachova, Wei-Ting Hung, Lynda K. McGinnis, Lane K. Christenson
    Pages 109-127
  6. Marco Conti, João Pedro Sousa Martins, Seung Jin Han, Federica Franciosi
    Pages 129-156
  7. Hervé Prats, Christian Touriol
    Pages 157-180
  8. Fernando F. Blanco, Noémie Legrand, Cyril Sobolewski, Dan A. Dixon
    Pages 181-219
  9. Wen-Jun Shen, Zhigang Hu, Jie Hu, Fredric B. Kraemer, Salman Azhar
    Pages 253-275
  10. Faoud T. Ishmael, Cristiana Stellato
    Pages 277-313
  11. Alexandra M. Amen, Daniel L. Pham, Mollie K. Meffert
    Pages 315-337
  12. Back Matter
    Pages 339-341

About this book

Introduction

This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on disease and health are covered, providing a novel update to the scientific literature.
Post-transcriptional regulatory mechanisms play an essential role in controlling dynamic gene expression. The outcome of this regulation includes control of the amount, timing, and location of protein expression. Regulation is mediated by cis-acting RNA sequences and structures and transacting RNA binding proteins and non-coding RNAs, including microRNAs. Recent advances in characterization of these regulatory factors have revealed enormous regulatory potential.

Keywords

cytokines hormones insulin post-transcriptional regulation post-translational regulation steroid hormone receptor gene expression microRNA metabolism

Editors and affiliations

  • K.M.J. Menon, PhD
    • 1
  • Aaron Goldstrohm, PhD
    • 2
  1. 1.Departments of Biological Chemistry & Obstetrics and Gynecology University of Michigan Medical SchoolAnn ArborUSA
  2. 2.Department of Biological ChemistryUniversity of Michigan Medical SchoolAnn ArborUSA

Bibliographic information