Essentials of Cerebellum and Cerebellar Disorders

A Primer For Graduate Students

  • Donna L. Gruol
  • Noriyuki Koibuchi
  • Mario Manto
  • Marco Molinari
  • Jeremy D. Schmahmann
  • Ying Shen

Table of contents

  1. Front Matter
    Pages i-x
  2. Donna L. Gruol, Noriyuki Koibuchi, Mario Manto, Marco Molinari, Jeremy D. Schmahmann, Ying Shen
    Pages 1-2
  3. Brief Historical Note

  4. Anatomy and Histology of the Cerebellum

    1. Front Matter
      Pages 31-31
    2. Jan Voogd, Enrico Marani
      Pages 33-38
    3. Qiaoshu Wang, Louis R. Caplan
      Pages 39-54
    4. Yuanjun Luo, Izumi Sugihara
      Pages 55-61
    5. Mayumi Yamada, Mikio Hoshino
      Pages 63-67
    6. Tom J. H. Ruigrok
      Pages 79-88
    7. Manuel Jan Roth, Axel Lindner, Peter Thier
      Pages 89-100
    8. Jeremy D. Schmahmann
      Pages 101-115
    9. Kim van Dun, Mario Manto, Peter Mariën
      Pages 117-123
  5. Embryology and Development of the Cerebellum

    1. Front Matter
      Pages 125-125
    2. Ketty Leto, Richard Hawkes, G. Giacomo Consalez
      Pages 127-135
    3. Carol Armstrong, Richard Hawkes
      Pages 137-141
    4. Mikio Hoshino
      Pages 143-147
    5. Hong-Ting Prekop, Richard J. T. Wingate
      Pages 149-154
    6. Marco Sassoè-Pognetto
      Pages 155-159
    7. Kouichi Hashimoto, Masahiko Watanabe, Masanobu Kano
      Pages 161-165
  6. Cerebellar Circuits: Biochemistry, Neurotransmitters and Neuromodulation

    1. Front Matter
      Pages 175-175
    2. Egidio D’Angelo
      Pages 177-182
    3. Anais Grangeray, Kevin Dorgans, Sebastien Roux, Jean-Louis Bossu
      Pages 183-188
    4. Siqiong June Liu, Christophe J. Dubois
      Pages 189-193
    5. Masahiko Watanabe
      Pages 195-199
    6. Stéphane Dieudonné
      Pages 201-205
    7. Moritoshi Hirono
      Pages 207-211
    8. Marco Martina, Gabriella Sekerková
      Pages 213-218
    9. Katharine L. Dobson, Tomas C. Bellamy
      Pages 219-223
    10. Tomoo Hirano
      Pages 225-229
    11. Susumu Tomita
      Pages 231-236
    12. Gerard Zitnik, Daniel J. Chandler, Barry D. Waterhouse
      Pages 237-241
    13. Marlies Oostland, Johannes A. van Hooft
      Pages 243-247
    14. Sho Kakizawa
      Pages 249-253
    15. Mark J. Wall
      Pages 261-266
    16. Georgia A. Bishop, James S. King
      Pages 267-272
    17. C. Fernando Valenzuela
      Pages 273-277
    18. Carla da Silva Matos, María Fernanda Vinueza Veloz, Tom J. H. Ruigrok, Chris I. De Zeeuw
      Pages 279-284
    19. Egidio D’Angelo
      Pages 285-290
  7. Basic Physiology

    1. Front Matter
      Pages 291-291
    2. Thomas S. Otis
      Pages 299-303
    3. Steven Dykstra, Ray W. Turner
      Pages 305-309
    4. Dieter Jaeger, Huo Lu
      Pages 311-315
    5. Ying Shen
      Pages 317-321
    6. Robin Broersen, Beerend H. J. Winkelman, Ozgecan Ozyildirim, Chris I. De Zeeuw
      Pages 323-327

About this book


Essentials of the Cerebellum and Cerebellar Disorders is the first book of its kind written specifically for graduate students and clinicians. It is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. This monograph makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from ataxia clinics and cerebellar laboratories throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.


Cerebellum Ataxias Brain Cerebellar cortex Cerebellar nuclei

Editors and affiliations

  • Donna L. Gruol
    • 1
  • Noriyuki Koibuchi
    • 2
  • Mario Manto
    • 3
  • Marco Molinari
    • 4
  • Jeremy D. Schmahmann
    • 5
  • Ying Shen
    • 6
  1. 1.Molecular and Cellular Neuroscience DepartmentThe Scripps Research InstituteLa JollaUSA
  2. 2.Department of Integrative PhysiologyGunma University Graduate School of MedicineMaebashiJapan
  3. 3.FNRS, ULB-ErasmeBruxellesBelgium
  4. 4.Clinical Translational ResearchSanta Lucia FoundationRomeItaly
  5. 5.Ataxia Unit, Cognitive Behavioral Neurology Unit, Laboratory for Neuroanatomy and Cerebellar Neurobiology, Department of Neurology Massachusetts General HospitalHarvard Medical SchoolBostonUSA
  6. 6.Department of NeurobiologyZhejiang University School of MedicineHangzhouChina

Bibliographic information