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Cancer Vaccines

  • Natalia Savelyeva
  • Christian Ottensmeier

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 405)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Sonia Quaratino, Ulf Forssmann, Jens-Peter Marschner
    Pages 1-31
  3. Emma King, Christian Ottensmeier, Kevin G. J. Pollock
    Pages 33-53
  4. Kimberly A. Kraynyak, Angela Bodles-Brakhop, Mark Bagarazzi
    Pages 55-78
  5. Bruce Acres, Gisele Lacoste, Jean-Marc Limacher
    Pages 79-97
  6. Federica Riccardo, Elisabetta Bolli, Marco Macagno, Maddalena Arigoni, Federica Cavallo, Elena Quaglino
    Pages 99-122
  7. Natalia Savelyeva, Alex Allen, Warayut Chotprakaikiat, Elena Harden, Jantipa Jobsri, Rosemary Godeseth et al.
    Pages 123-143
  8. Christian Grunwitz, Lena M. Kranz
    Pages 145-164
  9. Marcus Remer, Ann White, Martin Glennie, Aymen Al-Shamkhani, Peter Johnson
    Pages 165-207
  10. Back Matter
    Pages 209-210

About this book

Introduction

This volume focuses on the laboratory and clinical experience with targeting viral onco-antigens, while also reviewing the approaches to targeting self-cancer antigens in cancers of non-viral origin, where self-tolerance has been a challenge. It emphasizes the importance of selecting the right vaccine platform to induce a successful immune response against cancer antigens. In addition, the volume discusses the advances made with genetic vaccines, including recent advances with  DNA vaccines and the rapid transition of mRNA vaccines from the laboratory to bedside. The new avenues opening up for cancer immunotherapy underline the importance of combinational approaches using cancer vaccines with costimulatory antibodies, which may dramatically improve cancer treatment.
This book is intended for all translational researchers and clinicians who aspire to develop novel vaccination approaches for cancer patients with unmet clinical needs.

Keywords

Cancer therapeutics Electroporation Immune tolerance Immunotherapy Lung cancer HPV-induced cancers Muc1-expressing solid tumour Chimeric DNA vaccines mRNA cancer vaccines Anti-CD40 mAb

Editors and affiliations

  • Natalia Savelyeva
    • 1
  • Christian Ottensmeier
    • 2
  1. 1.Faculty of Medicine, Cancer Sciences UnitUniversity of SouthamptonSouthhamptonUnited Kingdom
  2. 2.Faculty of Medicine, Cancer Sciences UnitUniversity of Southampton SouthamptonUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-23910-1
  • Copyright Information Springer International Publishing AG 2017
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-23909-5
  • Online ISBN 978-3-319-23910-1
  • Series Print ISSN 0070-217X
  • Series Online ISSN 2196-9965
  • Buy this book on publisher's site