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Long Non-coding RNAs in Human Disease

  • Kevin V. Morris

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 394)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Francesca Aguilo, Serena Di Cecilia, Martin J. Walsh
    Pages 29-39
  3. Anna Roth, Sven Diederichs
    Pages 57-110
  4. Amy Leung, Kenneth Stapleton, Rama Natarajan
    Pages 127-141
  5. Charles E. Foulds, Anil K. Panigrahi, Cristian Coarfa, Rainer B. Lanz, Bert W. O’Malley
    Pages 143-176
  6. Marina C. Costa, Ana Lúcia Leitão, Francisco J. Enguita
    Pages 177-202
  7. Saba Valadkhan, Alberto Valencia-Hipólito
    Pages 203-236
  8. Back Matter
    Pages 259-262

About this book

Introduction

This volume focuses on the roles of long non-coding RNAs (lncRNAs) in contexts ranging from human cancers to cardiovascular disease and ageing. The role of lncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, past retroelements integrated within the human genome, as well as the role these pseudogene-derived lncRNAs play in cancer development are discussed in detail. Further, the book examines the function of lncRNAs in diseases such as diabetes, in smooth muscle formation, and in the modulation of nuclear receptors, as well as in connection with perspectives on the development of personalized therapeutics. It offers an appealing and insightful resource for scientists and clinicians alike.

Keywords

T-cell mediated immunity Cellular stress response Epigenetic loss-of-function disease Nuclear hormone receptors Prostrate cancer Tumor suppressor genes LncRNA Pseudogene-expressed RNAs Exosome associated lncRNAs ANRIL Polycomb Pseudogene-expressed RNAs Non-protein-coding transcriptome

Editors and affiliations

  • Kevin V. Morris
    • 1
  1. 1.City of Hope - Beckman Research InstituteCenter for Gene Therapy City of Hope-Beckman Research InstituteDuarteUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-23907-1
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-23906-4
  • Online ISBN 978-3-319-23907-1
  • Series Print ISSN 0070-217X
  • Series Online ISSN 2196-9965
  • Buy this book on publisher's site