© 2016

Applying Comparative Effectiveness Data to Medical Decision Making

A Practical Guide

  • Carl Asche

Table of contents

  1. Front Matter
    Pages i-viii
  2. Nikhil R. Kalva, James F. Graumlich
    Pages 13-25
  3. Jaeyong Bae, Carl V. Asche
    Pages 27-35
  4. Jinma Ren
    Pages 37-51
  5. Minchul Kim, Carl V. Asche, Inkyu K. Kim
    Pages 63-81
  6. Matt Mischler, Jessica Hanks
    Pages 97-113

About this book


This textbook introduces students to the basic concepts and methods used to measure and compare the expected benefits, risks and cost of preventive and therapeutic medical interventions. It provides an easily accessible overview of comparative effectiveness and its practical applications to daily medical decisions. The book includes learning objectives for each topic, definitions of key terms and topic summaries. Each chapter is written by a highly regarded academic and extensive reference is made throughout to other sources of literature where the interested reader can find further details.

The book considers, among other topics, evidence based medicine and the role of comparative effectiveness research in the development of medical guidelines, bias and confounding, quality of life, randomized controlled trials, analyses of retrospective databases, screening and economic evaluation. The book is intended to serve as a “what is it?”, “why do we need it?” and “how does it or could it effect positive change in health care?” rather than just a “how to?” technical overview. As such, it provides an essential resource for both under- and post-graduate students in health sciences.


Economic evaluation Observational data Patient-reported outcomes Randomised clinical trials Retrospective databases Screening

Editors and affiliations

  • Carl Asche
    • 1
  1. 1.Affiliate Faculty, Center for Pharmacoepidemiology and Pharmacoeconomic Research, University of Illinois at Chicago College of PharmacyResearch Professor, Director of Center for Outcomes Research, Department of Pharmacy Systems, Outcomes and PolicyChicagoUSA

About the editors

Dr. Carl Asche is the Director of the Center for Outcomes Research at the University of Illinois College of Medicine at Peoria, where he is a Research Professor both in the Departments of Medicine (Peoria) and Pharmacy Systems, Outcomes & Policy (Chicago). He is also a research affiliate with the University of Victoria Centre on Aging. His research focuses on the use of comparative effectiveness research and cost-effectiveness analysis in health care decision making. In addition to the present book,his academic work has comprised authoring or co-authoring of over 75 papers that appear in the medical and economic literature. He has presented his research at seminars and conferences both nationally and internationally. He has served on numerous national and international health economics focused editorial, grant review, advisory boards and committees. Dr. Asche’s research is funded by a variety of state/federal agencies and health system providers. 

Bibliographic information

  • Book Title Applying Comparative Effectiveness Data to Medical Decision Making
  • Book Subtitle A Practical Guide
  • Editors Carl Asche
  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Adis, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-319-22064-2
  • Softcover ISBN 978-3-319-79376-4
  • eBook ISBN 978-3-319-23329-1
  • Edition Number 1
  • Number of Pages VIII, 113
  • Number of Illustrations 4 b/w illustrations, 12 illustrations in colour
  • Topics Pharmacoeconomics and Health Outcomes
  • Buy this book on publisher's site


“This is essential reading for researchers and healthcare professionals involved in making medical decisions, including physicians, midlevel practitioners, pharmacists, nurses, and other allied health professionals. … This is a thorough review of evidence-based medicine concepts and comparative effectiveness research that is easy to understand and offers a framework to support readers in determining how these concepts can be incorporated into their decision making methods in a practical and purposeful way.” (Valerie D. Barnes, Doody's Book Reviews, September, 2016)