Biologics to Treat Substance Use Disorders

Vaccines, Monoclonal Antibodies, and Enzymes

  • Ivan D.¬†Montoya

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Vaccines

    1. Front Matter
      Pages 5-5
    2. Coreen B. Domingo, Daryl Shorter, Thomas R. Kosten
      Pages 25-36
    3. Michael D. Raleigh, Paul R. Pentel
      Pages 37-63
    4. Thomas R. Kosten, Therese A. Kosten
      Pages 65-74
    5. Timothy Cardozo, Sergey V. Shmelkov, Kenneth Carr, John Rotrosen, Pedro Mateu-Gelabert, Samuel R. Friedman
      Pages 75-103
  3. Monoclonal Antibodies

    1. Front Matter
      Pages 105-105
    2. S. Michael Owens
      Pages 107-108
    3. Hanna N. Wetzel, William J. Ball, Andrew B. Norman
      Pages 109-117
    4. Michael D. Hambuchen, Misty W. Stevens, Melinda G. Gunnell, W. Brooks Gentry, S. Michael Owens
      Pages 119-142
  4. Enzymes

    1. Front Matter
      Pages 143-143
    2. W. Stephen Brimijoin
      Pages 167-185
    3. Fang Zheng, Chang-Guo Zhan
      Pages 187-225
  5. Strategies to Optimize the Development of Biologics to Treat Addictions

    1. Front Matter
      Pages 227-227
    2. David F. Havlicek, Jonathan B. Rosenberg, Dolan Sondhi, Ronald G. Crystal, Stephen M. Kaminsky
      Pages 229-248
    3. Petr O. Ilyinskii, Lloyd P. M. Johnston
      Pages 249-278
    4. Xiaowei Liu, Sidney M. Hecht, Hao Yan, Paul R. Pentel, Yung Chang
      Pages 279-293
    5. Frank M. Orson, Berma M. Kinsey, Reetakshi Arora, Muthu Ramakrishnan, Thomas R. Kosten
      Pages 295-307
    6. Xinyuan Chen, Ji Wang, Jeffrey H. Wu, Mei X. Wu
      Pages 309-325
    7. Karen C. Collins, Kim D. Janda
      Pages 327-365
  6. Practical Considerations

    1. Front Matter
      Pages 395-395
    2. Oscar B. Torres, Carl R. Alving, Arthur E. Jacobson, Kenner C. Rice, Gary R. Matyas
      Pages 397-424
  7. Back Matter
    Pages 439-453

About this book


This book is a scientific compendium documenting the state of the art in the discovery and development of vaccines, monoclonal antibodies, and enzymes for the treatment of Substance Use Disorders (SUDs). The book gives detailed consideration to some of the most cutting edge topics in addiction medicine, including vaccines for nicotine, cocaine, heroin, and methamphetamine dependence; monoclonal antibodies against cocaine, methamphetamine, and phencyclidine; and the enzymes butyrylcholinesterase and cocaine esterase. In addition, the text covers a wide range of new strategies designed to optimize the development and efficacy of biologics. Unlike any other resource, this book reviews how biologics offer exciting new therapeutic opportunities for various psychiatric conditions.

Written by experts in the field, Biologics to Treat Substance Use Disorders is as an authoritative reference for psychiatrists, psychologists, and all other medical professionals working with patients suffering from Substance Use Disorders.


Biologics Drug Addiction Enzymes Monoclonal Antibodies Substance Abuse Vaccines

Editors and affiliations

  • Ivan D.¬†Montoya
    • 1
  1. 1.National Institute on Drug AbuseNational Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-23149-5
  • Online ISBN 978-3-319-23150-1
  • Buy this book on publisher's site