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LIFE - AS A MATTER OF FAT

Lipids in a Membrane Biophysics Perspective

  • Ole G. Mouritsen
  • Luis A. Bagatolli

Part of the The Frontiers Collection book series (FRONTCOLL)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. The Overlooked Molecules

    1. Front Matter
      Pages 1-1
    2. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 3-17
    3. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 19-30
    4. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 31-44
    5. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 45-53
    6. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 55-64
    7. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 65-73
    8. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 75-81
  3. Lipids Make Sense

    1. Front Matter
      Pages 83-83
    2. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 85-93
    3. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 95-110
    4. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 111-123
    5. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 125-142
    6. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 143-150
    7. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 151-159
  4. Lipids in Action

    1. Front Matter
      Pages 161-161
    2. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 163-171
    3. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 173-187
    4. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 189-194
    5. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 195-202
    6. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 203-209
    7. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 211-222
    8. Ole G. Mouritsen, Luis A. Bagatolli
      Pages 223-237
  5. Back Matter
    Pages 239-298

About this book

Introduction

The present book gives a multi-disciplinary perspective on the physics of life and the particular role played by lipids (fats) and the lipid-bilayer component of cell membranes. The emphasis is on the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Furthermore, it is shown how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nanotechnology and biomedicine are also described.

 

The first edition of the present book was published in 2005 when lipidomics was still very much an emerging science and lipids about to be recognized as being as important for life as proteins, sugars, and genes. This significantly expanded and revised edition takes into account the tremendous amount of knowledge gained over the past decade.  In addition, the book now includes more tutorial material on the biochemistry of lipids and the principles of lipid self-assembly.

 

The book is aimed at undergraduate students and young research workers within physics, chemistry, biochemistry, molecular biology, nutrition, as well as pharmaceutical and biomedical sciences.

 

From the reviews of the first

edition:

 

"This is a highly interesting book and a pleasure to read. It represents a new and excellent pedagogical introduction to the field of lipids and the biophysics of biological membranes. I reckon that physicists and chemists as well as biologists will benefit from this approach to the field and Mouritsen shows a deep insight into the physical chemistry of lipids." (Göran Lindblom, Chemistry and Physics of Lipids 2005, vol. 135, page 105-106)

 

"The book takes the reader on an exciting journey through the lipid world, and Mouritsen attracts the attention with a lively style of writing … . a comprehensive view of the ‘lipid sea’ can be easily achieved, gaining the right perspectives for envisaging future developments in the nascent field of lipidomics." (Carla Ferreri, ChemBioChem, Vol. 6 (8), 2005)

Keywords

Biological Membranes Fatty Acids Lipid-bilayer of Cell Membranes Lipidomics Introduction Lipids in Bilayers Lipids in Nano-technology and Biomedicine Physical Properties of Lipid Membranes Textbook Biological Membranes

Authors and affiliations

  • Ole G. Mouritsen
    • 1
  • Luis A. Bagatolli
    • 2
  1. 1.Dept. of Physics, Chemistry and PharmacyMEMPHYS-Center for Biomembrane PhysicsOdenseDenmark
  2. 2.Department Biochemistry and Molecular BiologyMEMPHYS-Center for Biomembrane PhysicsOdenseDenmark

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-22614-9
  • Copyright Information Springer International Publishing Switzerland 2016
  • Publisher Name Springer, Cham
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-3-319-22613-2
  • Online ISBN 978-3-319-22614-9
  • Series Print ISSN 1612-3018
  • Series Online ISSN 2197-6619
  • Buy this book on publisher's site