Waldenström’s Macroglobulinemia

  • Véronique Leblond
  • Steve Treon
  • Meletios Dimoploulos

Table of contents

  1. Front Matter
    Pages i-ix
  2. Tumor Cells and Microenvironment

    1. Front Matter
      Pages 1-1
    2. Roger G. Owen, Andy C. Rawstron, Ruth M. de Tute
      Pages 3-19
    3. Noemí Puig, Enrique M. Ocio, Cristina Jiménez, Bruno Paiva, Jesús F. San Miguel, Ramón García-Sanz
      Pages 21-34
    4. Linda M. Pilarski, Jitra Kriangkum, Sophia Adamia, Helga M. Ogmundsdottir, Andrew R. Belch
      Pages 35-48
    5. Florence Nguyen-Khac
      Pages 49-51
    6. Zachary R. Hunter, Guang Yang, Lian Xu, Xia Liu, Jorge J. Castillo, Steven P. Treon
      Pages 53-65
    7. Antonio Sacco, Michele Moschetta, Salomon Manier, Giuseppe Rossi, Irene M. Ghobrial, Aldo M. Roccaro
      Pages 67-71
    8. Efstathios Kastritis, Aldo Roccaro, Magdalini Migou, Irene Ghobrial
      Pages 73-82
    9. D. E. Joshua, R. Brown, P. J. Ho, J. Gibson, H. Suen
      Pages 83-94
  3. Epidemiology and Genetic Predisposition

    1. Front Matter
      Pages 95-95
    2. Vilhjálmur Steingrímsson, Ola Landgren, Sigurður Yngvi Kristinsson
      Pages 97-109
    3. Mary L. McMaster, Helga M. Ögmundsdóttir
      Pages 111-141
    4. Mary L. McMaster, Helga M. Ögmundsdóttir, Sigurdur Y. Kristinsson, Robert A. Kyle
      Pages 143-167
  4. Clinical Features

    1. Front Matter
      Pages 169-169
    2. Karine Viala, Michael Lunn
      Pages 185-194
    3. Morie A. Gertz, Taimur Sher, Angela Dispenzieri, Francis K. Buadi
      Pages 195-207
    4. K. Ina Ly, Florian Fintelmann, Reza Forghani, Ephraim P. Hochberg, Fred H. Hochberg
      Pages 209-221
    5. Giampaolo Merlini, Bouchra Asli, Jean-Paul Fermand
      Pages 223-236
  5. Laboratory Investigations

    1. Front Matter
      Pages 237-237
    2. Guillemette Fouquet, Stéphanie Poulain, Suzanna Schraen, Efstathios Koulieris, Elisabeth Bertrand, Stéphanie Guidez et al.
      Pages 239-261
  6. Response

    1. Front Matter
      Pages 263-263
    2. Eva Kimby, Roger G. Owen, Enrica Morra
      Pages 265-275
  7. Prognostic Factors

    1. Front Matter
      Pages 277-277
    2. Pierre Morel, Bénédicte Hivert
      Pages 279-293
  8. Treatment Options and Recommendations

    1. Front Matter
      Pages 295-295
    2. Robert A. Kyle, Stephen M. Ansell, Prashant Kapoor
      Pages 297-313
    3. Véronique Leblond, Laetitia Souchet, Sylvain Choquet, Christian Buske
      Pages 315-326
    4. Steven P. Treon, Guang Yang, Zachary R. Hunter, Jorge J. Castillo
      Pages 327-334
    5. Steven P. Treon, Jorge J. Castillo, Efstathios Kastritis, Meletios A. Dimopoulos
      Pages 335-343
    6. Enrica Morra, Anna Maria Frustaci, Paola Picardi, Antonino Greco, Alessandra Tedeschi
      Pages 357-365
    7. Véronique Leblond, Meletios A. Dimopoulos, Steven P. Treon
      Pages 367-370
  9. Back Matter
    Pages 371-377

About this book


This book sheds new light on clinical, biological and therapeutic data on the rare disease Waldenström’s Macroglobulinemia (WM) with the participation of widely-recognized experts, involved in this field. It represents the efforts of physicians, scientists and patients, all around the world, to better understand and cure this rare disease.

Considerable advances in the diagnosis, treatment indications, response criteria, prognostic factors and treatment options have been made since Dr Jan Waldenström first reported this “new syndrome“ 70 years ago. Particularly instrumental in advancing of our understanding of WM have been the eight  international workshops devoted to this disease. New, exciting molecular data have recently been reported, allowing us to revisit the oncogenic events leading to WM B-cell proliferation and to use newly available compounds targeting oncogenic pathways.


Chemotherapy Chronic disease Immunotherapy Lymphoma Monoclonal IgM Orphan disease

Editors and affiliations

  • Véronique Leblond
    • 1
  • Steve Treon
    • 2
  • Meletios Dimoploulos
    • 3
  1. 1.HaematologyHôpital Pitié-SalpêtriêreParisFrance
  2. 2.Dana Farber Cancer InstituteBostonUSA
  3. 3.School of MedicineUniversity of AthensAthensGreece

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2017
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-22583-8
  • Online ISBN 978-3-319-22584-5
  • Buy this book on publisher's site