RNA/DNA and Cancer

  • Joseph G. Sinkovics

Table of contents

  1. Front Matter
    Pages i-xi
  2. Joseph G. Sinkovics
    Pages 1-28
  3. The Primordial RNA/DNA Complex Evolving

    1. Front Matter
      Pages 29-29
    2. Joseph G. Sinkovics
      Pages 35-49
    3. Joseph G. Sinkovics
      Pages 111-120
    4. Joseph G. Sinkovics
      Pages 121-130
    5. Joseph G. Sinkovics
      Pages 131-135
    6. Joseph G. Sinkovics
      Pages 137-141
    7. Joseph G. Sinkovics
      Pages 181-187
    8. Joseph G. Sinkovics
      Pages 189-199
    9. Joseph G. Sinkovics
      Pages 207-246
    10. Joseph G. Sinkovics
      Pages 247-250
    11. Joseph G. Sinkovics
      Pages 251-256
    12. Joseph G. Sinkovics
      Pages 257-290
    13. Joseph G. Sinkovics
      Pages 291-297
    14. Joseph G. Sinkovics
      Pages 299-330
  4. The Oncogenome

    1. Front Matter
      Pages 331-331
    2. Joseph G. Sinkovics
      Pages 407-423
    3. Joseph G. Sinkovics
      Pages 425-438
  5. The Human Cerebral Cortical DNA Against Cancer DNA

  6. Back Matter
    Pages 559-815

About this book


In this book, the author Joseph G. Sinkovics liberally shares his views on the cancer cell which he has been observing in vivo and in vitro, over a life time. Readers will learn how, as an inherent faculty of the RNA/DNA complex, the primordial cell survival pathways are endogenously reactivated in an amplified or constitutive manner in the multicellular host, and are either masquerading as self-elements or as placentas, to which the multicellular host is evolutionarily trained to extend full support. The host obliges.

 The author explains that there is no such evidence that “malignantly transformed” human cells survive in nature. However, when cared for in the laboratory, these cells live and replicate as immortalized cultures. These cells retain their vitality upon storage in liquid nitrogen. One can only imagine an astrophysical environment in which such cells could survive; perhaps, first their seemingly humble exosomes would populate that environment. Immortal cell populations so created may survive as individuals, or may even re-organize themselves into multicellular colonies, as representatives of life for the duration of the Universe.

 This thought-provoking book is the work of a disciplined investigator and clinician with an impeccable reputation, and he enters a territory that very few if any before him have approached from the same angles. It will appeal to researchers with an interest in cell survival pathways and those researching cancer cells. 


ancient eukaryotic cell survival pathways cancer immunology/immunotherapy cancer virology oncolytic viruses proto-oncogenes/oncogenes

Authors and affiliations

  • Joseph G. Sinkovics
    • 1
  1. 1.The University of TexasRetired Professor, M.D. Anderson Hospital Comprehensive Cancer CenterHoustonUSA

Bibliographic information