Edge-to-Edge Mitral Repair

From a Surgical to a Percutaneous Approach

  • Ottavio Alfieri
  • Michele De Bonis
  • Giovanni La Canna

Table of contents

  1. Front Matter
    Pages i-viii
  2. Ottavio Alfieri
    Pages 1-6
  3. Francesco Sturla, Emiliano Votta, Maurizio Taramasso, Andrea Guidotti, Alberto Redaelli, Francesco Maisano
    Pages 7-18
  4. Andrea Fumero, Michele De Bonis
    Pages 19-29
  5. Giovanna Di Giannuario, Emanuela Alati, Giovanni La Canna
    Pages 43-64
  6. Roberto Lorusso, Enrico Vizzardi, Sandro Gelsomino
    Pages 65-73
  7. Michele De Bonis, Elisabetta Lapenna, Gabriele Del Castillo, Ottavio Alfieri
    Pages 75-91
  8. Giovanna Di Giannuario, Giovanni La Canna
    Pages 99-109
  9. Elisabetta Lapenna, Davide Schiavi, Gabriele Del Castillo, Michele De Bonis
    Pages 121-128
  10. Stefano Benussi, Alberto Pozzoli, Maurizio Taramasso, Paolo Denti
    Pages 129-135
  11. Paolo Denti, Nicola Buzzatti, Giovanni La Canna
    Pages 137-146
  12. Maurizio Taramasso, Alberto Pozzoli, Antonio Colombo
    Pages 147-156
  13. Paolo Denti, Nicola Buzzatti, Francesco Maisano
    Pages 157-164
  14. Ottavio Alfieri
    Pages 165-166

About this book


​This is the first comprehensive review of the edge-to-edge technique for mitral repair, which was introduced into the surgical armamentarium in 1991 by one of the authors, Ottavio Alfieri. The surgical technique employed in edge-to-edge repair today provides the basis for the only reliable method of percutaneous correction of degenerative mitral regurgitation. The book traces the evolution of the edge-to-edge technique from a surgical to a percutaneous approach, documenting indications, contraindications, technical aspects, controversies, and clinical outcomes. Detailed attention is devoted to the MitraClip procedure, which reproduces the Alfieri stitch percutaneously and has to date been used in more than 20,000 patients worldwide. The state of the art in MitraClip therapy is described, with clear explanation of when and how to use the MitraClip system. The reader will learn all aspects of percutaneous edge-to-edge repair, which is recommended for use in carefully selected patients in the new ESC/EACTS guidelines for the management of valvular heart disease and in the ESC guidelines on heart failure. The group at San Raffaele Hospital, Milan, has accumulated by far the largest experience in the world with the technique and over the years has been very active in its promotion and scientific evaluation. This book reflects that depth of knowledge and will be of great interest to cardiac surgeons and interventional and clinical cardiologists.


MitraClip Mitral regurgitation Mitral stenosis Mitral valve Percutaneous mitral repair

Editors and affiliations

  • Ottavio Alfieri
    • 1
  • Michele De Bonis
    • 2
  • Giovanni La Canna
    • 3
  1. 1.Department of Cardiac SurgerySan Raffaele HospitalMilanItaly
  2. 2.Department of Cardiac SurgerySan Raffaele HospitalMilanItaly
  3. 3.Department of Cardiac SurgerySan Raffaele HospitalMilanItaly

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-319-19892-7
  • Online ISBN 978-3-319-19893-4
  • Buy this book on publisher's site