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Immune Responses to Biosurfaces

Mechanisms and Therapeutic Interventions

  • John D. Lambris
  • Kristina N. Ekdahl
  • Daniel Ricklin
  • Bo Nilsson

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 865)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Mechanisms

    1. Front Matter
      Pages 1-1
    2. Kristina N. Ekdahl, Yuji Teramura, Sana Asif, Nina Jonsson, Peetra U. Magnusson, Bo Nilsson
      Pages 3-17
    3. Diana Karpman, Anne-lie Ståhl, Ida Arvidsson, Karl Johansson, Sebastian Loos, Ramesh Tati et al.
      Pages 19-42
    4. Markus Huber-Lang, Anita Ignatius, Rolf E. Brenner
      Pages 43-55
    5. George Hajishengallis, Tomoki Maekawa, Toshiharu Abe, Evlambia Hajishengallis, John D. Lambris
      Pages 57-74
  3. Biomaterials

    1. Front Matter
      Pages 75-75
    2. Estrid Hein, Peter Garred
      Pages 77-92
    3. Michail Kastellorizios, Namita Tipnis, Diane J. Burgess
      Pages 93-108
    4. Laura Beth Moore, Themis R. Kyriakides
      Pages 109-122
    5. Jeffrey L. Platt, Lucile E. Wrenshall, Geoffrey B. Johnson, Marilia Cascalho
      Pages 123-140
  4. Transplantation

    1. Front Matter
      Pages 141-141
    2. Bruno Reichart, Sonja Guethoff, Paolo Brenner, Thomas Poettinger, Eckhard Wolf, Barbara Ludwig et al.
      Pages 143-155
    3. Ioannis Kourtzelis, Peetra U. Magnusson, Klara Kotlabova, John D. Lambris, Triantafyllos Chavakis
      Pages 171-188
    4. Yuji Teramura, Sana Asif, Kristina N. Ekdahl, Bo Nilsson
      Pages 189-209
  5. Back Matter
    Pages 235-242

About these proceedings

Introduction

​The collection of chapters in this proceedings volume brings together research from academic and industry scientists and clinical development experts who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical outcome. Optimal tissue integration and modulation of foreign body reactions is therefore essential for preserving anticipated functions and avoiding adverse effects. Topics covered include mechanistic and applied research within the fields of extracorporeal devices, soft and hard tissue implants, tissue and biomaterial-targeting, therapeutic modulation of foreign body reactions, cell encapsulations, as well as cell and whole organ transplantation.

Keywords

biomaterials biomedical implant cell surface cell therapy immune response organ transplantation

Editors and affiliations

  • John D. Lambris
    • 1
  • Kristina N. Ekdahl
    • 2
  • Daniel Ricklin
    • 3
  • Bo Nilsson
    • 4
  1. 1.Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA
  2. 2.Immunology, Genetics and PathologyUniversity of UppsalaUppsalaSweden
  3. 3.Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA
  4. 4.Immunology, Genetics and PathologyUniversity of UppsalaUppsalaSweden

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-319-18603-0
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-18602-3
  • Online ISBN 978-3-319-18603-0
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site