Reducing Mortality in Critically Ill Patients

  • Giovanni Landoni
  • Marta Mucchetti
  • Alberto Zangrillo
  • Rinaldo Bellomo

Table of contents

  1. Front Matter
    Pages i-vi
  2. Massimiliano Greco, Marialuisa Azzolini, Giacomo Monti
    Pages 1-6
  3. Interventions that Reduce Mortality

    1. Front Matter
      Pages 7-7
    2. Luca Cabrini, Margherita Pintaudi, Nicola Villari, Dario Winterton
      Pages 9-21
    3. Antonio Pisano, Teresa P. Iovino, Roberta Maj
      Pages 23-29
    4. Antonio Pisano, Luigi Verniero, Federico Masserini
      Pages 31-38
    5. Annalisa Volpi, Silvia Grossi, Roberta Mazzani
      Pages 39-45
    6. Łukasz J. Krzych
      Pages 47-52
    7. Christopher G. Hughes, Pratik P. Pandharipande, Timothy D. Girard
      Pages 53-59
  4. Interventions that Increase Mortality

    1. Front Matter
      Pages 61-61
    2. Cosimo Chelazzi, Zaccaria Ricci, Stefano Romagnoli
      Pages 63-71
    3. Rasmus B. Müller, Nicolai Haase, Anders Perner
      Pages 73-78
    4. Nigel R. Webster
      Pages 79-82
    5. Stefano Romagnoli, Giovanni Zagli, Zaccaria Ricci
      Pages 83-91
    6. Kate C. Tatham, C. Stephanie Cattlin, Michelle A. Hayes
      Pages 93-101
    7. Laura Pasin, Pasquale Nardelli, Alessandro Belletti
      Pages 111-115
    8. Laura Pasin, Pasquale Nardelli, Desiderio Piras
      Pages 117-122
  5. Updates

    1. Front Matter
      Pages 123-123
    2. Marta Mucchetti, Livia Manfredini, Evgeny Fominskiy
      Pages 125-132
    3. Hesham R. Omar, Devanand Mangar, Enrico M. Camporesi
      Pages 133-140

About this book


This book describes the techniques, strategies, and drugs that have been demonstrated by multicenter randomized trials to influence survival in critically ill patients, defined as those who have acute failure of at least one organ, due to either a pathological condition or a medical intervention, and require intensive care treatment. Each chapter focuses on a specific procedure, device, or drug. The scope is accordingly wide, with coverage of topics as diverse as noninvasive mechanical ventilation, protective ventilation, prone positioning, intravenous salbutamol in ARDS, high-frequency oscillatory ventilation, mild hypothermia after cardiac arrest, daily interruption of sedatives, tranexamic acid, diaspirin cross-linked hemoglobin, albumin, growth hormone, glutamine supplementation, tight glucose control, supranormal oxygen delivery, and hydroxyethyl starch in sepsis. The topic selection was made using a democracy-based approach in which hundreds of specialists from dozens of countries expressed, via the web, whether they agreed with these topics and whether they used the techniques in their daily clinical practice. The clear text is supported by "how to do" sections and "key point" boxes that provide easily accessible practical information. The book will be of interest for a wide variety of specialists, including intensivists, emergency doctors, and anesthesiologists.


Acute respiratory distress syndrome Democratic-based medicine Emergency medicine Intensive care Sepsis / septic shock Survival

Editors and affiliations

  • Giovanni Landoni
    • 1
  • Marta Mucchetti
    • 2
  • Alberto Zangrillo
    • 3
  • Rinaldo Bellomo
    • 4
  1. 1.Department of Anesthesia and Intensive careIRCCS San Raffaele Scientifi c InstituteMilanItaly
  2. 2.Department of Anesthesia and Intensive careIRCCS San Raffaele Scientific InstituteMilanItaly
  3. 3.San Raffaele HospitalMilanItaly
  4. 4.Department of Intensive CareAustin HospitalHeidelberg, Vic. 3084Australia

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-17514-0
  • Online ISBN 978-3-319-17515-7
  • Buy this book on publisher's site