Resistance to Immunotoxins in Cancer Therapy

  • Rama Shanker Verma
  • Benjamin Bonavida

Part of the Resistance to Targeted Anti-Cancer Therapeutics book series (RTACT, volume 6)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Sudarshan Gadadhar, Anjali A. Karande
    Pages 1-31
  3. Sithambaram Devilakshmi, Jayaprakasam Madhumathi, Rama Shanker Verma
    Pages 33-56
  4. Sebastian Stahl, Fabian Mueller, Ira Pastan, Ulrich Brinkmann
    Pages 57-73
  5. Roland B. Walter
    Pages 75-87
  6. Christian Cremer, Grit Hehmann-Titt, Sonja Schiffer, Georg Melmer, Paolo Carloni, Stefan Barth et al.
    Pages 185-219
  7. Back Matter
    Pages 247-249

About this book


This volume is a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted therapy. As well, it includes an in-depth description of the molecular and cellular mechanisms involved in cancer resistance and several novel methods to overcome resistance. Each chapter discusses different aspects of resistance and covers all the factors that may contribute to resistance in cancer cells. Finally, this volume highlights the recent findings and advances associated with tackling cancer resistance.


antibodies chemoresistance drug development drug resistance immunotoxin resistance

Editors and affiliations

  • Rama Shanker Verma
    • 1
  • Benjamin Bonavida
    • 2
  1. 1.Department of BiotechnologyIndian Institute of Technology MadrasChennaiIndia
  2. 2.Department of Microbiology, Immunology,University of California of Los AngelesLos AngelesUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-319-17274-3
  • Online ISBN 978-3-319-17275-0
  • Series Print ISSN 2196-5501
  • Series Online ISSN 2196-551X
  • Buy this book on publisher's site