Lung Stem Cells in the Epithelium and Vasculature

  • Amy Firth
  • Jason X.-J. Yuan

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Airway Stem Cells

    1. Front Matter
      Pages 1-1
    2. Samriddha Ray, Barry R. Stripp
      Pages 3-12
    3. Thomas J. Lynch, Xiaoming Liu, Jun Wei, John F. Engelhardt
      Pages 35-58
    4. Michael Hiatt, Orquidea Garcia, Amber Lundin, Barbara Driscoll
      Pages 59-70
    5. Ena Ray Banerjee, William Reed Henderson Jr.
      Pages 71-91
    6. Fernanda F. Cruz, Patricia R. M. Rocco, Daniel J. Weiss
      Pages 93-112
    7. Tushar Menon, Amy L. Firth
      Pages 113-143
    8. Darcy E. Wagner, Franziska E. Uhl, Melanie Königshoff, Daniel J. Weiss
      Pages 145-180
  3. Pulmonary Vasculature Stem Cells

    1. Front Matter
      Pages 181-181
    2. Kewal Asosingh, Jonathan Rose, Serpil Erzurum
      Pages 183-192
    3. Radhika Dixit, Xingbin Ai, Alan Fine
      Pages 193-201
    4. Lauren Hartman, Troy Stevens
      Pages 203-219
    5. Alice Huertas, Marc Humbert, Christophe Guignabert
      Pages 241-256
    6. Kelley L. Colvin, Ozus Lohani, Michael E. Yeager
      Pages 257-276
    7. Amy L. Firth, Jason X.-J. Yuan
      Pages 277-287
    8. Quentin Felty, Seiijiro Sakao, Norbert F. Voelkel
      Pages 289-306
    9. Glenn Marsboom, Min Zhang, Jalees Rehman, Asrar B. Malik
      Pages 307-326
  4. Back Matter
    Pages 343-345

About this book


This book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as ex vivo lung bioengineering. Such approaches may provide novel therapeutic approaches for lung diseases. Human pluripotent stem cell differentiation to model the pulmonary epithelium and vasculature is also discussed.

World-recognized scientists who specialize in studying both the lung epithelium and pulmonary vasculature contribute the chapters. Topics covered include: stem cell niches in the lung, the role of progenitor cells in fibrosis and asthma, iPSC in modeling lung disease, vascular repair by endothelial progenitor cells and circulating fibrocytes in pulmonary vascular remodeling. This volume of the Stem Cell Biology and Regenerative Medicine series is essential reading for researchers and clinicians interested in stem cells, lung biology and regenerative medicine. It is also an invaluable resource for advanced students studying cell biology, regenerative medicine and lung physiology.


Clara cells Progenitor cells Pulmonary hypertension Stem cells Vascular remodeling

Editors and affiliations

  • Amy Firth
    • 1
  • Jason X.-J. Yuan
    • 2
  1. 1.Laboratory of GeneticsSalk Institute for Biological StudiesLa JollaUSA
  2. 2.Department of MedicineThe Univsersity of ArizonaTucsonUSA

Bibliographic information