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Textbook of Cell Signalling in Cancer

An Educational Approach

  • Jacques Robert

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Jacques Robert
    Pages 27-41
  3. Jacques Robert
    Pages 43-54
  4. Jacques Robert
    Pages 55-65
  5. Jacques Robert
    Pages 67-76
  6. Jacques Robert
    Pages 77-92
  7. Jacques Robert
    Pages 93-100
  8. Jacques Robert
    Pages 101-107
  9. Jacques Robert
    Pages 109-115
  10. Jacques Robert
    Pages 117-126
  11. Jacques Robert
    Pages 127-139
  12. Jacques Robert
    Pages 141-151
  13. Jacques Robert
    Pages 153-163
  14. Jacques Robert
    Pages 165-177
  15. Jacques Robert
    Pages 179-189
  16. Jacques Robert
    Pages 191-201
  17. Jacques Robert
    Pages 203-219
  18. Jacques Robert
    Pages 221-240
  19. Back Matter
    Pages 241-328

About this book

Introduction

This book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis.

This comprehensive reference text is based on the master’s courses delivered by Prof. Jacques Robert to graduate students at the University of Bordeaux, France. It includes a large number of colour schemas and figures that have been improved year after year for educational purposes. Signalling pathways are described individually and in depth, but without ignoring the multiplicity of interconnections and crosstalk. The presentation of each pathway is followed by a brief description of the alterations found in cancers as well as of the targeted pharmacological approaches that can be used to prevent or overcome the consequences of these oncogenic alterations. The basic mechanisms of molecular biology at the DNA replication, RNA transcription and protein activity levels are presented in a series of didactic annexes, enabling readers to better understand the alterations in signalling pathways.

Keywords

cancer cell cycle cell proliferation oncology signaling pathways

Authors and affiliations

  • Jacques Robert
    • 1
  1. 1.Institut BergoniéBordeauxFrance

Bibliographic information