Molecular Mechanisms Underpinning the Development of Obesity

  • Clévio Nóbrega
  • Raquel Rodriguez-López

Table of contents

  1. Front Matter
    Pages i-xii
  2. Thorkild I.A. Sørensen
    Pages 1-7
  3. Hèléne Huvenne, Béatrice Dubern
    Pages 9-21
  4. David Albuquerque, Clévio Nóbrega
    Pages 37-55
  5. David Albuquerque, Licínio Manco, Clévio Nóbrega
    Pages 101-127
  6. Lígia Sousa-Ferreira, Luís Pereira de Almeida, Cláudia Cavadas
    Pages 129-152
  7. Goro Katsuura, Namiko Kawamura, Miyuki Nishida, Haruka Amitani, Akihiro Asakawa, Akio Inui
    Pages 153-166
  8. George N. Chaldakov, Luigi Aloe, Anton B. Tonchev, Marco Fiore
    Pages 167-178
  9. Charbel Abi Khalil, Shahrad Taheri
    Pages 179-194

About this book


Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The book provides a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, while also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.


GWAS development diabetes genetics molecular mechanisms obesity

Editors and affiliations

  • Clévio Nóbrega
    • 1
  • Raquel Rodriguez-López
    • 2
  1. 1.Cntr for Neurosciences and Cell Biology University of CoimbraCoimbraPortugal
  2. 2.Nutrition and Gastroenterology DepartmentArmand-Trousseau HospitalValenciaSpain

Bibliographic information