Practical Protein Bioinformatics

  • Florencio Pazos
  • Mónica Chagoyen

Table of contents

  1. Front Matter
    Pages i-viii
  2. Florencio Pazos, Mónica Chagoyen
    Pages 1-41
  3. Florencio Pazos, Mónica Chagoyen
    Pages 43-83
  4. Florencio Pazos, Mónica Chagoyen
    Pages 85-99
  5. Back Matter
    Pages 101-106

About this book


This book describes more than 60 web-accessible computational tools for protein analysis and is totally practical, with detailed explanations on how to use these tools and interpret their results and minimal mentions to their theoretical basis (only when that is required for making a better use of them). It covers a wide range of tools for dealing with different aspects of proteins, from their sequences, to their three-dimensional structures, and the biological networks they are immersed in. The selection of tools is based on the experience of the authors that lead a protein bioinformatics facility in a large research centre, with the additional constraint that the tools should be accessible through standard web browsers without requiring the local installation of specific software, command-line tools, etc.

The web tools covered include those aimed to retrieve protein information, look for similar proteins, generate pair-wise and multiple sequence alignments of protein sequences, work with protein domains and motifs, study the phylogeny of a family of proteins, retrieve, manipulate and visualize protein three-dimensional structures, predict protein structural features as well as whole three-dimensional structures, extract biological information from protein structures, summarize large protein sets, study protein interaction and metabolic networks, etc.

The book is associated to a dynamic web site that will reflect changes in the web addresses of the tools, updates of these, etc. It also contains QR codes that can be scanned with any device to direct its browser to the tool web site.

This monograph will be most valuable for researchers in experimental labs without specific knowledge on bioinformatics or computing.


protein bioinformatics protein networks protein sequences wet methods

Authors and affiliations

  • Florencio Pazos
    • 1
  • Mónica Chagoyen
    • 2
  1. 1.National Centre for Biotechnology (CNB-CSIC)MadridSpain
  2. 2.National Centre for Biotechnology (CNB-CSIC)MadridSpain

Bibliographic information