Cardiovascular Imaging

Arterial and Aortic Valve Inflammation and Calcification

  • Elena Aikawa

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Preclinical Imaging of Mechanisms of Atherosclerosis and Its Complications

    1. Front Matter
      Pages 1-1
    2. Thibaut Quillard, Kevin J. Croce
      Pages 3-38
    3. Jun-ichiro Koga, Masanori Aikawa
      Pages 65-78
    4. Eric A. Osborn, Farouc A. Jaffer
      Pages 79-106
    5. Karen Briley-Saebo, Calvin Yeang, Joel R. Wilson, Sotirios Tsimikas
      Pages 121-154
    6. Sara McArdle, Ekaterina Koltsova, Grzegorz Chodaczek, Klaus Ley
      Pages 155-170
  3. Imaging Insights into Mechanisms of Calcific Aortic Valve Disease (CAVD) and Calcification

    1. Front Matter
      Pages 185-185
    2. Joshua D. Hutcheson, Elena Aikawa
      Pages 187-199
    3. Alex Thomas Vesey, Marc Richard Dweck, David Ernest Newby
      Pages 201-223
    4. Jason P. Linefsky, Catherine M. Otto
      Pages 225-249
    5. Yu Nomura, Kengyeh K. Chu, Joseph A. Gardecki, Chen-hsin Sun, Linbo Liu, Eduardo Martinez-Martinez et al.
      Pages 251-265
  4. Clinical Imaging of Cardiovascular Inflammation and Calcification

    1. Front Matter
      Pages 267-267
    2. Rik P. M. Moonen, Gustav J. Strijkers, Zahi A. Fayad, Mat J. A. P. Daemen, Klaas Nicolay
      Pages 269-296
    3. Marcelo F. Di Carli
      Pages 297-326
    4. Hamed Emami, Ahmed Tawakol
      Pages 327-353
    5. Nobuhiro Tahara, Atsuko Tahara, Sho-ichi Yamagishi
      Pages 355-379
  5. Back Matter
    Pages 381-389

About this book


This book provides comprehensive reviews on our most recent understanding of the molecular and cellular mechanisms underlying atherosclerosis and calcific aortic valve disease (CAVD) as visualized in animal models and patients using optical molecular imaging, PET-CT, ultrasound, and MRI. In addition to presenting up-to-date information on the multimodality imaging of specific pro-inflammatory or pro-calcification pathways in atherosclerosis and CAVD, the book addresses the intriguing issue of whether cardiovascular calcification is an inflammatory disease, as has been recently supported by several preclinical and clinical imaging studies. In order to familiarize researchers and clinicians from other specialties with the basic mechanisms involved, chapters on the fundamental pathobiology of atherosclerosis and CAVD are also included. The imaging chapters, written by some of the foremost investigators in the field, are so organized as to reveal the nature of the involved mechanisms as disease progresses.


Calcification Cardiovascular Diagnostic Radiology Inflammation Multimodality Imaging

Editors and affiliations

  • Elena Aikawa
    • 1
  1. 1.Cardiovascular MedicineBrigham and Women’s Hospital Harvard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer International Publishing Switzerland 2015
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-319-09267-6
  • Online ISBN 978-3-319-09268-3
  • Buy this book on publisher's site