Stem Cells in Animal Species: From Pre-clinic to Biodiversity

  • Tiziana A.L. Brevini

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Stem Cells for Pre-clinical Models

    1. Front Matter
      Pages 1-1
    2. Clemetina Sitzia, Silvia Erratico, Andrea Farini, Yvan Torrente, Mirella Meregalli
      Pages 3-30
    3. Iolanda Aquila, Carla Vicinanza, Mariangela Scalise, Fabiola Marino, Christelle Correale, Michele Torella et al.
      Pages 31-48
    4. Anjali Nandal, Bhanu Prakash V. L. Telugu
      Pages 49-68
    5. Anna Lange-Consiglio, Fausto Cremonesi
      Pages 69-105
  3. Stem Cells in “Non-conventional” Species

    1. Front Matter
      Pages 107-107
    2. Tiziana A. L. Brevini, Sara Maffei, Fulvio Gandolfi
      Pages 143-147
  4. Stem Cell Banking for the Future

    1. Front Matter
      Pages 149-149
    2. Ida Biunno, Pasquale DeBlasio
      Pages 151-166
    3. Sara Maffei, Tiziana A. L. Brevini, Fulvio Gandolfi
      Pages 167-184
  5. Back Matter
    Pages 185-186

About this book


This volume focuses on stem cell research and disease modeling in non-murine species. The book is divided into three parts: Stem Cells for Pre-Clinical Models, Stem Cells in Non-Conventional Species, and Stem Cell Banking for the Future. The first section presents an overview of the different pre-clinical stem cell models recently created in animal species, including the porcine model for heart failure, iPSC in large animal species, Duchenne muscular dystrophy and canine embryo-derived stem cells and modeling for human diseases. This section also discusses the potential advantages and applications of these models.

The second part of this book describes recent efforts to use stem cells for preserving endangered species, including the snow leopard and coral reefs. From this perspective, stem cells are an invaluable tool to preserve bio-diversities. Frozen cells and gametes can be obtained from animals at risk of extinction and even from microorganisms and corals suffering from heavy changes in the eco-system; this may allow the cultivation of a generation of stem cell lines and represents an exciting opportunity to support and ensure the conservation of precious varieties of living creatures. This discussion leads easily into the third section, which discusses stem cell banking as a way of safeguarding these endangered species.


Duchenne Muscular dystrophy canine embryo-derived porcine model stem cell banking

Editors and affiliations

  • Tiziana A.L. Brevini
    • 1
  1. 1.Università degli Studi di MilanoLaboratory of Biomedical Embriology; Unistem; Centre for Stem Cell ResearchMilanItaly

Bibliographic information