Oxidative Stress and Neuroprotection

  • H. Parvez
  • P. Riederer

Part of the Journal of Neural Transmission. Supplementa book series (NEURALTRANS, volume 71)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. H. Reichmann, P. Odin, H. M. Brecht, J. Köster, P. H. Kraus
    Pages 17-25
  3. T. Muüller, J. Welnic, G. Fuchs, H. Baas, G. Ebersbach, H. Reichmann
    Pages 27-30
  4. E. Sofic, A. Sapcanin, I. Tahirovic, I. Gavrankapetanovic, K. Jellinger, G. P. Reynolds et al.
    Pages 39-43
  5. M. Minami, N. Hamaue, M. Hirafuji, H. Saito, T. Hiroshige, A. Ogata et al.
    Pages 87-95
  6. A. Medvedev, O. Buneeva, O. Gnedenko, V. Fedchenko, M. Medvedeva, Y. Ivanov et al.
    Pages 97-103
  7. J. O’Sullivan, M. I. O’Sullivan, K. F. Tipton, G. Davey
    Pages 105-112
  8. P. A. LeWitt
    Pages 113-122
  9. K. Magyar, M. Pálfi, V. Jenei, É. Szökő
    Pages 143-156
  10. A. H. V. Schapira
    Pages 157-161
  11. S. L. Clardy, X. Wang, W. Zhao, W. Liu, G. A. Chase, J. L. Beard et al.
    Pages 173-196

About this book

Introduction

This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson’s disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson’s therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.

Keywords

Alzheimer Morbus Parkinson Parkinson alzheimer's disease apoptosis brain cell cytokine dementia depression influence neuroprotection oxidative stress physiology regulation

Editors and affiliations

  • H. Parvez
    • 1
  • P. Riederer
    • 2
  1. 1.Institute Alfred Fessard de NeurosciencesCNRSGif YvetteFrance
  2. 2.Klinik und Poliklinik für Psychiatrie und PsychotherapieWürzburgGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-211-33328-0
  • Copyright Information Springer-Verlag/Wien 2006
  • Publisher Name Springer, Vienna
  • eBook Packages Medicine
  • Print ISBN 978-3-211-33327-3
  • Online ISBN 978-3-211-33328-0
  • About this book