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Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo

  • David Raeburn
  • Mark A. Giembycz

Part of the Respiratory Pharmacology and Pharmacotherapy book series (RPP)

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Steve Webber, Jan-Anders Karlsson
    Pages 1-25
  3. Stephen L. Underwood, David Raeburn
    Pages 27-50
  4. Aileen A. Y. Milne, Adriano G. Rossi, Ian D. Chapman
    Pages 51-73
  5. James G. Martin, Hideyasu Mishima
    Pages 75-93
  6. Wil H. M. Stevens, Paul M. O’Byrne
    Pages 95-119
  7. David B. Jacoby
    Pages 121-145
  8. Caroline M. Herd, Clive P. Page
    Pages 147-169
  9. William M. Abraham
    Pages 171-189
  10. Claudia R. Turner, John W. Watson
    Pages 191-223
  11. Adrian Tomkinson
    Pages 225-240
  12. Robert Schilz, Jack A. Elias
    Pages 241-274
  13. Back Matter
    Pages 275-276

About this book

Introduction

Building on the existing titles in the "Airways Smooth Muscle" sub-series, the sixth volume explores physiological and pharmacological processes in the lung in vivo. The various animal models available for studying the bronchospasm and inflammation associated with human asthma are thoroughly reviewed by internationally recognised scientists. Specific chapters focus on the problems of administering drugs to animal airways, the mechanics of assessing lung function in the models, and describe in detail the species used, from rodents to primates. The use of genetically altered animals, an area of particular interest to molecular biologists, is also considered in depth. This up-to-date and extensively referenced work will prove invaluable to pharmacologists, physiologists and other biological scientists at all levels in academia and in the pharmaceutical industry.

Keywords

Antigen Asthma-Forschung Glatte Muskulatur der Atemwege asthma drug inflammation research smooth muscle

Editors and affiliations

  • David Raeburn
    • 1
  • Mark A. Giembycz
    • 2
  1. 1.Discovery BiologyRhône-Poulenc Rorer Ltd Dagenham Research CentreEssexEngland
  2. 2.Department of Thoracic MedicineNational Heart and Lung Institute Imperial College of Science, Technology and MedicineLondonEngland

Bibliographic information