Airway Mucus: Basic Mechanisms and Clinical Perspectives

  • Duncan F. Rogers
  • Michael I. Lethem

Part of the Respiratory Pharmacology and Pharmacotherapy book series (RPP)

Table of contents

  1. Front Matter
    Pages I-X
  2. John G. Widdicombe
    Pages 1-17
  3. David J. Thornton, Julia R. Davies, Ingemar Carlstedt, John K. Sheehan
    Pages 19-39
  4. Mary Callaghan Rose, Sandra J. Gendler
    Pages 41-66
  5. Terence M. Newman, Duncan F Rogers
    Pages 67-89
  6. Michael J. Sanderson
    Pages 91-116
  7. Gary J. Phillips, Stuart L. James, Michael I. Lethem
    Pages 117-147
  8. C. William Davis
    Pages 149-177
  9. Denis C. K. Fung, Duncan F. Rogers
    Pages 179-210
  10. Charlotte Rayner, Robert Wilson
    Pages 211-225
  11. Dechun Li, Peter K. Jeffery
    Pages 227-273
  12. Edith Puchelle, Jean-Marie Zahm, Sophie de Bentzmann, Dominique Gaillard
    Pages 301-326
  13. Bayan Abdul-Haq, Gary P. Martin, Christopher Marriott
    Pages 327-339
  14. Myra Stern, Eric W. Alton
    Pages 341-364
  15. Atsushi Yuta, James N. Baraniuk
    Pages 365-383
  16. Back Matter
    Pages 385-388

About this book


Conceptually unsavoury, airway mucus is vital to homeostasis in the respiratory tract. In contrast, when abnormal, mucus contributes significantly to the pathophysiology of a number of severe bronchial diseases, including asthma, chronic bronchitis and cystic fibrosis. This volume provides wide ranging and in-depth coverage of the scientific and clinical aspects of airway mucus. It commences with introductory chapters which address the biochemical and molecular biological basis of airway mucus and continues with comprehensive coverage of the various physiological and rheological aspects of respiratory secretions. The clinical aspects of the topic are then considered, with chapters discussing the involvement of mucus secretions in bacterial infection and in hypersecretory diseases of the airway. The volume concludes with a discussion of the therapeutic aspects of the topic, both in terms of the possible approaches to the treatment of mucus hypersecretion and the interaction of these drugs with airway mucus. Written by leading experts in the field, each contribution provides a comprehensive review of its particular subject. Reflecting the latest advances in this important area of respiratory research, this volume will be of great interest to scientists and clinicians working in the field of airway secretions and related areas.


Atmen Respiratory research asthma bacteria bacterial infection biochemistry biology cell gene infection microbiology pathophysiology physiology research

Editors and affiliations

  • Duncan F. Rogers
    • 1
  • Michael I. Lethem
    • 2
  1. 1.Department of Thoracic Medicine National Heart and Lung InstituteImperial College of Science, Technology and MedicineLondonEngland
  2. 2.Department of PharmacyUniversity of BrightonBrightonEngland

Bibliographic information