• Nicolas J. Goulding
  • Rod J. Flower

Part of the Milestones in Drug Therapy MDT book series (MDT)

Table of contents

  1. Front Matter
    Pages I-X
  2. The development of glucocorticoids as therapeutic agents

    1. Front Matter
      Pages 1-1
    2. Nicolas J. Goulding, Roderick J. Flower
      Pages 3-15
  3. Molecular mechanisms of glucocorticoid action

    1. Front Matter
      Pages 53-53
    2. Fotini Paliogianni, Dimitrios T. Boumpas
      Pages 81-101
  4. Current perspectives in glucocorticoid biology

    1. Front Matter
      Pages 103-103
    2. Costantino Pitzalis, Niccoló Pipitone, Mauro Perretti
      Pages 105-118
    3. Jamie D. Croxtall
      Pages 119-127
    4. Anne-Marie Cowell, Julia C. Buckingham
      Pages 129-145
    5. Marc B. Feinstein, Robert P. Schleimer
      Pages 147-158
  5. Glucocorticoids in contemporary clinical practice

    1. Front Matter
      Pages 159-159
    2. John H. Toogood
      Pages 161-173
    3. John R. Kirwan
      Pages 175-190
    4. Filip J. Baert, Paul R. Rutgeerts
      Pages 191-200
  6. Back Matter
    Pages 201-205

About this book


Following 50 years of glucocorticoid use in a clinical setting, an international body of expert scientists and physicians presents the most expansive survey of glucocorticoid pharmacology to date. This work traces the history of glucocorticoid biology from the seminal description of glucocorticoid insufficiency by Thomas Addison in the mid-19th century, up to current advances in elucidating the molecular basis of glucocorticoid action. Important discoveries are presented, as well as milestones in drug development, a survey of current clinical practice, and prospects for novel glucocorticoid-based therapeutics. Scientists and clinicians will appreciate the scope of this work, which is of special interest to workers in the fields of endocrinology, inflammation and autoimmune disease.


autoimmune disease biology drug drug development endocrinology glucocorticoid inflammation pharmacology

Editors and affiliations

  • Nicolas J. Goulding
    • 1
  • Rod J. Flower
    • 1
  1. 1.Dept of Biochemical Pharmacology William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen MaryUniversity of LondonLondonUK

Bibliographic information