Inflammation and Stroke

  • Giora Z. Feuerstein

Part of the Progress in Inflammation Research book series (PIR)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Inflammation in stroke and CNS trauma — experimental and clinical evidence

  4. Inflammatory and immune responses to CNS injury: beneficial and detrimental components

    1. Front Matter
      Pages 35-35
    2. Philipp M. Lenzlinger, Thomas Kossmann, Tracy K. McIntosh, Maria Cristina Morganti-Kossmann
      Pages 49-60
  5. Inflammatory cells in stroke

    1. Front Matter
      Pages 75-75
    2. Dwaine F. Emerich, Reginald L. Dean III, Raymond T. Bartus
      Pages 77-88
  6. Inflammatory cytokines, interleukins and chemokines in stroke and CNS trauma

    1. Front Matter
      Pages 113-113
    2. John R. Bethea, Ricardo Prado, W. Dalton Dietrich
      Pages 141-154
    3. Elaine E. Peters, Giora Z. Feuerstein
      Pages 155-162
    4. V. Wee Yong, Richard M. Ransohoff
      Pages 181-191
  7. Inflammation in cerebral thrombosis, angiogenesis and matrix regulation: a new perspective in stroke research and therapeutics

    1. Front Matter
      Pages 193-193
    2. Daniel C. Morris, Michael Chopp
      Pages 221-240
  8. Inflammatory proteases and oxygen radicals in stroke

    1. Front Matter
      Pages 263-263
    2. Yvan Gasche, Jean-Christophe Copin, Pak H. Chan
      Pages 265-274
    3. Ariel Miller, Yaara Ben-Yosef, Clara Braker, Sarah Shapiro
      Pages 275-285
    4. Bernhard H. J. Juurlink
      Pages 299-312
  9. Inflammatory adhesion molecules, kinins, nitric oxide complement factors and lipid mediators in stroke

    1. Front Matter
      Pages 313-313
    2. David J. Pinsky, E. Sander Connolly Jr
      Pages 315-331
    3. Nikolaus Plesnila, Jane Relton
      Pages 333-342
    4. Xinkang Wang, Costantino Iadecola, Giora Z. Feuerstein
      Pages 343-350
  10. Back Matter
    Pages 351-356

About this book


Stroke is a leading cause of death in developed countries. However, current therapeutic strategies for stroke have been largely unsuccessful. One possible explanation is that research and pharmacological management have focused on very early events in brain ischemia. New research has shown that brain ischemia and trauma elicit strong inflammatory reactions driven by both external and brain cells. The recognition of inflammation as a fundamental response to brain ischemia provides novel opportunities for new anti-inflammatory therapies. For the first time, an international body of researchers presents the latest findings about the cellular and humoral aspects of immune and inflammatory reactions in the brain. The work may have an impact on the treatment of neuroinjuries and ancillary brain diseases, and increase the understanding of the roles infections and immune reactions play in the brain milieu.


Inflammation research ancillary brain diseases brain cognition immunology inflammation neuroinjury research stroke trauma

Editors and affiliations

  • Giora Z. Feuerstein
    • 1
  1. 1.Cardiovascular Diseases Research Experimental StationDuPont Pharmaceuticals CompanyWilmingtonUSA

Bibliographic information