HMG-CoA Reductase Inhibitors

  • Gerd Schmitz
  • Michael Torzewski

Part of the Milestones in Drug Therapy MDT book series (MDT)

Table of contents

  1. Front Matter
    Pages I-X
  2. Stefano Bellosta, Rodolfo Paoletti, Alberto Corsini
    Pages 1-17
  3. Margaret E. Brousseau, Ernst J. Schaefer
    Pages 19-34
  4. Jörg Kotzka, Wilhelm Krone, Dirk Müller-Wieland
    Pages 35-54
  5. Helena K. Gylling, Tatu A. Miettinen
    Pages 121-133
  6. Back Matter
    Pages 149-151

About this book


HMG-CoA reductase inhibitors (statins) are established drugs for the treatment of hypercholesterolemia. Furthermore, they induce regression of vascular atherosclerosis as well as reduction of cardiovascular-related morbidity and death in patients with and without coronary artery disease. This book deals with statins which have substantially altered the approach to therapy of atherosclerosis and its sequelae. Emphasis is placed on the scientific background to the discoveries and the development of the therapy, including an overview of the current state of knowledge of the drugs. Clinical data are reviewed extensively. This book not only provides the reader with valuable information but also stimulates further research into the pathogenesis of atherosclerosis and the mechanisms behind the action of effective statins. It sets the stage for creative thinking among scientists of many disciplines for the accomplishment of our ultimate goals in treating atherosclerosis and its sequelae. This topical volume...


atherosclerosis cardiovascular coronary artery disease heart research

Editors and affiliations

  • Gerd Schmitz
    • 1
  • Michael Torzewski
    • 2
  1. 1.Institute for Clinical Chemistry and Laboratory MedicineUniversity RegensburgRegensburgGermany
  2. 2.Johannes Gutenberg-Universität Mainz KlinikumInstitut für Klinische Chemie und LaboratoriumsmedizinMainzGermany

Bibliographic information