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Oxidative Stress, Cell Activation and Viral Infection

  • C. Pasquier
  • R. Y. Olivier
  • C. Auclair
  • Lester Packer

Part of the Molecular and Cell Biology Updates book series (MCBU)

Table of contents

  1. Front Matter
    Pages I-XI
  2. K. Nose, M. Ohba, M. Shibanuma, T. Kuroki
    Pages 21-34
  3. B. M. Hannigan, S. Ranjbar, L. Cromie
    Pages 59-63
  4. A. Azzi, D. Boscoboinik, E. Chatelain, Nesrin K. Özer, Barbara Stäuble
    Pages 131-141
  5. G. Rotilio, L. Knoepfel, C. Steinkuhler, A. T. Palamara, M. R. Ciriolo, E. Garaci
    Pages 143-153
  6. D. Bonnefont-Rousselot, B. Arrio, J. Catudioc, L. Packer
    Pages 165-171
  7. M. Merad-Boudia, L. Fideler, A. Nicole, B. Aral, P. M. Sinet, P. Briand et al.
    Pages 173-192
  8. M. Meyer, R. Schreck, J. M. Müller, P. A. Baeuerle
    Pages 217-235
  9. N. H. Hunt, D. M. van Reyk, J. C. Fragonas, T. M. Jeitner, S. D. Goldstone
    Pages 237-251
  10. M. Gerbert, J. Dornand
    Pages 253-273
  11. W. Dröge, H.-P. Eck, S. Mihm, D. Galter
    Pages 285-299
  12. R. Olivier, O. Lopez, M. Mollereau, T. Dragic, D. Guetard, L. Montagnier
    Pages 323-332
  13. E. Postaire, L. Massias, O. Lopez, M. Mollereau, G. Hazebroucq
    Pages 333-340
  14. C. Sergeant, M. Simonoff, C. Hamon, E. Peuchant, M. F. Dumon, M. Clerc et al.
    Pages 341-351
  15. Back Matter
    Pages 353-362

About this book

Introduction

Since the appearance of photosynthesis on our planet, all living organisms have been facing a new abundant, extremely reactive element, oxygen. This element is used for the synthesis of highly energetic compounds, but can also generate molecules capable of damaging constituents of living structures, including proteins, nucleic acids and lipids. It is therefore no surprise that all biological organisms have evolved multiple and sophisticated ways to reduce the detrimental effects of oxygen. For cells and tissues of highly organized animals, particularly cells of the immune system, superoxidation products play an important role, via oxidative stress, in activation, inflammation and viral and bacterial infections. We must be grateful to Drs. C. Pasquier, C. Auclair, L. Packer and R. Olivier for having brought together many specialists in an international meeting held in Paris in March 1993, at the Ministry of Research. This book comprises an impressive amount of recent knowledge, a real mine for the reader in this fast developing field of research. Furthermore, we should not forget that this basic research may lead in the future to new therapeutic approaches to the most important pathologies of the latter part of this century, including AIDS.

Keywords

AIDS Activation bacteria cell immune system nucleic acid oxidative stress pathology protein proteins tissue

Editors and affiliations

  • C. Pasquier
    • 1
  • R. Y. Olivier
    • 2
  • C. Auclair
    • 3
  • Lester Packer
    • 4
  1. 1.INSERM U. 294ParisFrance
  2. 2.Dept. SIDA & RétrovirusUnité d’Oncologie ViraleParisFrance
  3. 3.Institut Gustave RoussyINSERM U. 140Villejuif CedexFrance
  4. 4.Dept. of Molecular and Cell Biology, 251 Life Science AdditionMembrane Bioenergetics GroupBerkeleyUSA

Bibliographic information