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Serotonin: Molecular Biology, Receptors and Functional Effects

  • John R. Fozard
  • Pramod R. Saxena

Table of contents

  1. Front Matter
    Pages i-xi
  2. Molecular Pharmacology, Cell Biology, Binding Sites and Receptors

    1. Front Matter
      Pages 1-1
    2. S. J. Peroutka
      Pages 3-4
    3. J. M. Palacios, C. Waeber, G. Mengod, M. Pompeiano
      Pages 5-20
    4. T. Branchek, J. Zgombick, M. Macchi, P. Hartig, R. Weinshank
      Pages 21-32
    5. B. L. Roth, M. W. Hamblin, R. Desai, R. D. Ciaranello
      Pages 33-42
    6. P. M. Whitaker-Azmitia, E. C. Azmitia
      Pages 43-49
    7. F. C. Zhou, E. C. Azmitia
      Pages 50-68
    8. M. Hamon, S. El Mestikawy, M. Riad, H. Gozlan, G. Daval, D. Vergé
      Pages 95-106
    9. D. Hoyer, H. Boddeke, P. Schoeffter
      Pages 117-132
    10. M. D. Gershon, P. R. Wade, E. Fiorica-Howells, A. L. Kirchgessner, H. Tamir
      Pages 133-143
    11. D. J. Prentice, V. J. Barrett, S. J. MacLennan, G. R. Martin
      Pages 161-173
    12. R. A. Glennon, S. J. Peroutka, M. Dukat
      Pages 186-191
    13. D. van Heuven-Nolsen, C. M. Villalón, M. O. den Boer, P. R. Saxena
      Pages 192-200
  3. Peripheral and Central Pharmacology

    1. Front Matter
      Pages 201-201
    2. D. I. Wallis, P. Elliott
      Pages 203-219
    3. C. M. Villalón, M. O. den Boer, J. P. C. Heiligers, P. R. Saxena
      Pages 253-263
    4. E. Hamel, D. Bouchard
      Pages 264-274
    5. D. Cambridge, M. V. Whiting, L. J. Butterfield
      Pages 282-288
  4. Pathophysiological Roles and Prospects for New Therapies

    1. Front Matter
      Pages 363-363
    2. A. J. Kaumann
      Pages 365-373
    3. G. J. Sanger, K. A. Wardle, S. Shapcott, K. F. Yee
      Pages 381-388
    4. L. M. Petrovic, S. A. Lorens, M. George, T. Cabrera, B. H. Gordon, R. J. Handa et al.
      Pages 389-397
    5. T. A. Kent, A. Jazayeri, J. M. Simard
      Pages 398-405
    6. F. C. Tanner, V. Richard, M. Tschudi, Z. Yang, T. F. Lüscher
      Pages 406-413
    7. P. P. A. Humphrey, W. Feniuk, M. Motevalian, A. A. Parsons, E. T. Whalley
      Pages 421-429
    8. J. E. Macor, C. A. Burkhart, J. H. Heym, J. L. Ives, L. A. Lebel, M. E. Newman et al.
      Pages 449-459
    9. T. Glaser, J. M. Greuel, E. Horvàth, R. Schreiber, J. De Vry
      Pages 460-470

About this book

Introduction

The Second IUPHAR Satellite Meeting on Serotonin was held under the auspices of the Serotonin Club in Basel, Switzerland in July 1990. The scope was wide, ranging from molecular biology through in vitro and in vivo pharmacology to new drug tools and their clinical signifi­ cance. There were three invited review lectures, by J. M. Palacios, D. I. Wallis and A. Kaumann, and S. Peroutka gave the first Serotonin Club Irvine H. Page Lecture. The rest of the oral programme was put together by the Scientific Organizing Committee based on volunteered research contributions. The invited review lecturers, the platform speak­ ers and selected poster contributors were invited to write up their contributions for inclusion in this volume. Most complied and this book is the result of their efforts. When instructing the authors prior to the meeting, we emphasized that selected new data should be put in the context of the literature findings. In this way we hoped to achieve topicality yet preserve the review perspective which facilitates its appreciation by the non-special­ ist. It was truly a pleasure to read the interesting papers which resulted and to prepare them for publication. We believe they convey to a remarkable degree the spirit of what was generally felt to be a highly stimulating exchange of information on matters serotonergic which took place in Basel last July.

Keywords

biology drug molecular biology pharmacology research serotonin

Editors and affiliations

  • John R. Fozard
    • 1
  • Pramod R. Saxena
    • 2
  1. 1.Preclinical ResearchSandoz Pharma Ltd.BaselSwitzerland
  2. 2.Institute of PharmacologyErasmus University RotterdamRotterdamThe Netherlands

Bibliographic information