Drugs Targeting B-Cells in Autoimmune Diseases

  • Xavier Bosch
  • Manuel Ramos-Casals
  • Munther A Khamashta

Part of the Milestones in Drug Therapy book series (MDT)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Martin S. Naradikian, Jean L. Scholz, Michael A. Oropallo, Michael P. Cancro
    Pages 11-35
  3. Maria Ahijón Lana, Zozik Fattah, Susana Araujo Fernandez, David A. Isenberg
    Pages 65-78
  4. Pilar Brito-Zerón, Ma José Soto-Cárdenas, Soledad Retamozo, Xavier Bosch, Manuel Ramos-Casals, Munther A. Khamashta
    Pages 79-95
  5. Stephan Blüml, Georg Stummvoll, Josef S. Smolen
    Pages 97-110
  6. Pilar Brito-Zerón, Antoni Sisó-Almirall, Belchin Kostov, Xavier Bosch, Athanasios G. Tzioufas, Manuel Ramos-Casals
    Pages 111-138
  7. Xavier Bosch, John H. Stone
    Pages 139-152
  8. Rohit Aggarwal, Vivek Nagaraja, Dinesh Khanna
    Pages 153-180
  9. Salvatore De Vita
    Pages 181-191
  10. Bassem N. Matta, Rabih Nayfe, Ali T. Taher, Imad Uthman
    Pages 193-217
  11. Maria Sepúlveda, Albert Saiz, Francesc Graus
    Pages 219-246
  12. Xavier Bosch, Pilar Brito-Zerón, Munther A. Khamashta, Manuel Ramos-Casals
    Pages 247-258
  13. Ian N. Bruce
    Pages 259-276
  14. Savino Sciascia, Dario Roccatello, Chary Lopez-Pedrera, Maria Jose’ Cuadrado
    Pages 277-284
  15. Back Matter
    Pages 285-292

About this book


This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases.


Cryoglobulinemia Inflammatory myopathies Rheumatoid arthritis Sjögren syndrome Systemic lupus erythematosus Systemic sclerosis Thrombosis Vasculitis

Editors and affiliations

  • Xavier Bosch
    • 1
  • Manuel Ramos-Casals
    • 2
  • Munther A Khamashta
    • 3
  1. 1.Hospital Clinic, Department of Internal MedicineUniversity of BarcelonaBarcelonaSpain
  2. 2.Department of Autoimmune DiseasesHospital ClinicBarcelonaSpain
  3. 3.King's College, The Rayne InstituteSt. Thomas' HospitalLondonUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Basel 2014
  • Publisher Name Springer, Basel
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-0348-0705-0
  • Online ISBN 978-3-0348-0706-7
  • Series Print ISSN 2296-6056
  • Series Online ISSN 2296-6064
  • Buy this book on publisher's site