Genomics of Pattern Recognition Receptors

Applications in Oncology and Cardiovascular Diseases

  • Anton G. Kutikhin
  • Arseniy E. Yuzhalin

Table of contents

  1. Front Matter
    Pages i-xi
  2. Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 33-55
  3. Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 57-76
  4. Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 77-100
  5. Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 101-121
  6. Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 123-151
  7. Anton G. Kutikhin, Arseniy E. Yuzhalin
    Pages 169-176
  8. Back Matter
    Pages 177-185

About this book

Introduction

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.

Keywords

Cancer Cardiovascular diseases Immune response NOD-like receptors Pathogen-associated patterns Toll-like receptors

Authors and affiliations

  • Anton G. Kutikhin
    • 1
  • Arseniy E. Yuzhalin
    • 2
  1. 1.EpidemiologyKemerovo State Medical AcademyKemerovoRussia
  2. 2.Res Inst Cardiovascular DiseasesRussian Academy of Medical Sciences Siberian BranchKemerovoRussia

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-0348-0688-6
  • Copyright Information Springer Basel 2013
  • Publisher Name Springer, Basel
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-0348-0687-9
  • Online ISBN 978-3-0348-0688-6
  • About this book