Immunosenescence

  • Andreas Thiel

Part of the Birkhäuser Advances in Infectious Diseases book series (BAID)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Nicola J. Booth, Arne N. Akbar, Milica Vukmanovic-Stejic
    Pages 1-23
  3. Chiara Romagnani
    Pages 25-36
  4. Henrik E. Mei, Andreas Radbruch
    Pages 55-84
  5. Fiona Powell, Florian Kern
    Pages 127-143
  6. Ulf Wagner
    Pages 145-155
  7. Birgit Weinberger, Beatrix Grubeck-Loebenstein
    Pages 157-174
  8. Wayne A. Mitchell, Ryan C. Pink, Antonio Lapenna, Richard Aspinall
    Pages 175-200
  9. Back Matter
    Pages 229-235

About this book

Introduction

As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in elderly persons. Therefore, age-associated dysfunctions of the humoral and cellular immune responses have a strong clinical impact. Improving our understanding of the aged immune system is crucial in developing effective prevention and treatment programs that will facilitate healthy aging and improve the quality of life of the elderly population.

The aim of this volume is to summarize current knowledge on the cellular and molecular aspects of the aging immune system, with an emphasis on infectious diseases and new therapeutic approaches.

Keywords

immune system immunology immunopathological disorders immunosenescence

Editors and affiliations

  • Andreas Thiel
    • 1
  1. 1.Campus Virchow-Klinikum, Berlin-Brandenburg Center forCharité - Universitätsmedizin BerlinBerlinGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-0346-0219-8
  • Copyright Information Springer Basel AG 2012
  • Publisher Name Springer, Basel
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-0346-0218-1
  • Online ISBN 978-3-0346-0219-8
  • About this book