© 2020

Cystic Fibrosis

A Multi-Organ System Approach

  • Stephanie Duggins Davis
  • Margaret Rosenfeld
  • James Chmiel

Part of the Respiratory Medicine book series (RM)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Jonathan D. Cogen, Bonnie W. Ramsey
      Pages 3-16
    3. Caroline S. Thomas, Clement L. Ren
      Pages 17-33
    4. Gabriela R. Oates, Michael S. Schechter
      Pages 35-55
  3. Pulmonary Manifestations

    1. Front Matter
      Pages 57-57
    2. Sarath C. Ranganathan
      Pages 59-72
    3. Valerie J. Waters, John J. LiPuma
      Pages 73-92
    4. Micheál Mac Aogáin, Céline Vidaillac, Sanjay H. Chotirmall
      Pages 93-126
    5. Thomas Ruffles, Claire Wainwright
      Pages 127-160
    6. Deepika Polineni, Dave Nichols, Alex H. Gifford
      Pages 161-179
    7. Kristina Montemayor, Allison A. Lambert, Natalie E. West
      Pages 181-198
    8. Shruti M. Paranjape, Peter J. Mogayzel Jr
      Pages 199-213
    9. Bryan Garcia, Jessica Mattson, Patrick A. Flume
      Pages 215-227
    10. Joseph M. Pilewski
      Pages 229-258
  4. Gastrointestinal Manifestations

    1. Front Matter
      Pages 259-259
    2. Amar Mandalia, Matthew J. DiMagno
      Pages 261-298
    3. Anna Bertolini, Frank A. J. A. Bodewes, Mordechai Slae, Michael Wilschanski
      Pages 299-320
    4. Adam C. Stein, Nicole Green, Sarah Jane Schwarzenberg
      Pages 321-334
  5. Other Organ System Manifestations

    1. Front Matter
      Pages 335-335

About this book


This book provides a comprehensive overview of the multisystem disease, cystic fibrosis, for both pediatric and adult patients.  Written by experts in the field, the text outlines the progressive nature of CF as well as the impact of this autosomal recessive disease on the respiratory, gastrointestinal, endocrine, rheumatologic, and renal systems, as well as the patient’s mental health.  The book begins with a chapter describing the history of cystic fibrosis and how the face of this life-shortening disease has changed over the past several decades.  The following chapters elucidate the pathophysiology of how cystic fibrosis impacts each organ system.  Current management and therapeutics are detailed with step-by-step guidelines for clinicians.  This book is unique in that it highlights the entire person, not just the respiratory system, with detailed inclusion of the patient perspectives throughout, informing practice standards and considerations. This is an ideal guide for pediatric and adult physicians who care for patients with cystic fibrosis, as well as respiratory therapists, physical therapists, nurses, nutritionists, and pharmacists who care for these patients.


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Editors and affiliations

  • Stephanie Duggins Davis
    • 1
  • Margaret Rosenfeld
    • 2
  • James Chmiel
    • 3
  1. 1.The University of North Carolina at Chapel Hill, Department of Pediatrics, UNC Children’s HospitalChapel HillUSA
  2. 2.Department of PediatricsUniversity of Washington School of Medicine, Division of Pulmonary and Sleep Medicine, Seattle Children’s HospitalSeattleUSA
  3. 3.Department of PediatricsIndiana University School of Medicine, Division of Pediatric Pulmonology, Allergy and Sleep Medicine, Riley Hospital for Children at IU HealthIndianapolisUSA

About the editors

Stephanie D Davis, MD is Professor of Pediatrics, Director of Pediatric Pulmonology, Allergy and Sleep Medicine, and Vice Chair of Clinical Affairs in the Department of Pediatrics at Indiana University School of Medicine. She is volume editor of another series book, Diagnostic Tests in Pediatric Pulmonology (2015).

Margaret Rosenfeld, MD, MPH is Professor of Pediatrics in the Division of Pulmonary Medicine and Associate Director of the Center for Clinical and Translational Research at Seattle Children’s Hospital.

James Chmiel, MD, MPH is Professor of Pediatrics in the Division of Pediatric Pulmonology, Allergy/Immunology and Sleep Medicine, Director of the Cystic Fibrosis Therapeutics Development Center, Associate Center Director of the LeRoy W. Matthews Cystic Fibrosis Center, and Director of the Pediatric Cystic Fibrosis Program at Case Western Reserve University School of Medicine and Rainbow Babies and Children’s Hospital.

Bibliographic information

  • Book Title Cystic Fibrosis
  • Book Subtitle A Multi-Organ System Approach
  • Editors Stephanie Duggins Davis
    Margaret Rosenfeld
    James Chmiel
  • Series Title Respiratory Medicine
  • Series Abbreviated Title Respiratory Medicine
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Humana, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-030-42381-0
  • Softcover ISBN 978-3-030-42384-1
  • eBook ISBN 978-3-030-42382-7
  • Series ISSN 2197-7372
  • Series E-ISSN 2197-7380
  • Edition Number 1
  • Number of Pages XVII, 526
  • Number of Illustrations 10 b/w illustrations, 26 illustrations in colour
  • Topics Pneumology/Respiratory System
  • Buy this book on publisher's site