Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

Antioxidant Therapeutic Defenses

  • Loutfy H. Madkour

Part of the Nanomedicine and Nanotoxicology book series (NANOMED)

Table of contents

About this book


This book provides insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. It presents the recent advances in new nanomedication technologies of the effects of nanoparticles NPs on oxidative stress, RONS and ER stress. The book comprises 13 chapters covering ecotoxicology, cytotoxicity, nanotoxicity and genotoxicity mechanisms causing by the role and interactions of nanoparticles and free radicals with (RONS) and (ER) stress. Endoplasmic Reticulum (ER) Stress as a mechanism for NPs induced toxicity has been discussed. The advances of nanotechnology and the effects of nanoparticles on oxidative stress, ROS and ER stress parameters are discussed. Antioxidants, therapeutic options and regulation of the immune responses are explained throughout the book.


Nanoparticles Reactive oxygen and nitrogen species Redox RONS Free radicals Endoplasmic Reticulum Stress ER Stress Ecotoxicology Nanotoxicology Oxidant Oxidative stress Oxidative damage Antioxidants Therapeutic defenses

Authors and affiliations

  1. 1.Physical Chemistry and Nanoscience, Department of Chemistry, Faculty of ScienceAl Baha UniversityBaljurashiSaudi Arabia

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-030-37296-5
  • Online ISBN 978-3-030-37297-2
  • Series Print ISSN 2194-0452
  • Series Online ISSN 2194-0460
  • Buy this book on publisher's site