Glioma Signaling

  • Jolanta Barańska

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1202)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Stefania Ceruti, Maria P. Abbracchio
    Pages 13-33
  3. Dorota Wypych, Jolanta Barańska
    Pages 35-65
  4. Dorota Wypych, Paweł Pomorski
    Pages 67-86
  5. Elizandra Braganhol, Márcia Rosângela Wink, Guido Lenz, Ana Maria Oliveira Battastini
    Pages 87-108
  6. Wanda Kłopocka, Jarosław Korczyński, Paweł Pomorski
    Pages 109-128
  7. Aneta Kwiatkowska, Marc Symons
    Pages 129-149
  8. Mitsutoshi Nakada, Daisuke Kita, Lei Teng, Ilya V. Pyko, Takuya Watanabe, Yutaka Hayashi et al.
    Pages 151-178
  9. Karolina Swiatek-Machado, Bozena Kaminska
    Pages 203-222
  10. Aleksandra Ellert-Miklaszewska, Iwona A. Ciechomska, Bozena Kaminska
    Pages 223-241
  11. Olena Karatsai, Oleh Stasyk, Maria Jolanta Redowicz
    Pages 243-258
  12. Iwona A. Ciechomska, Chinchu Jayaprakash, Marta Maleszewska, Bozena Kaminska
    Pages 259-279
  13. Myriam Catalano, Giuseppina D’Alessandro, Flavia Trettel, Cristina Limatola
    Pages 281-298
  14. Back Matter
    Pages 299-305

About this book


Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumor, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. This book is a reference on cellular signaling processes regulating gliomas physiology and invasiveness. 

The work is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides and formation of complex signaling cascades induced by growth factors, cytokines and cannabinoids. The second edition of the book enriched in new chapters provides a framework explaining how signal transduction elements may modulate numerous genetic and epigenetic alterations, describes the role of local microenvironment in cellular growth, progression and invasion and, in the light of extensive new results, presents perspectives concerning potential targets for gliomas therapy.


secondary messengers nucleotide receptors tumor growth tumor invasion tyrosine kinase receptors

Editors and affiliations

  • Jolanta Barańska
    • 1
  1. 1.BiochemistryNencki Institute of Experimental BiologyWarsawPoland

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-030-30650-2
  • Online ISBN 978-3-030-30651-9
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site