© 2020

Grand Challenges in Fungal Biotechnology

  • Helena Nevalainen

Part of the Grand Challenges in Biology and Biotechnology book series (GCBB)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Fungal Biotechnology and the Global Challenges

    1. Front Matter
      Pages 1-1
    2. Jack A. Whittaker, Robert I. Johnson, Tim J. A. Finnigan, Simon V. Avery, Paul S. Dyer
      Pages 59-79
    3. Ronald P. de Vries, Aleksandrina Patyshakuliyeva, Sandra Garrigues, Sheba Agarwal-Jans
      Pages 81-120
  3. Developments in Key Enabling Technologies

    1. Front Matter
      Pages 121-121
    2. Alexander Lichius, Dubraska Moreno Ruiz, Susanne Zeilinger
      Pages 123-164
    3. Kyle Rothschild-Mancinelli, Susanne M. Germann, Mikael R. Andersen
      Pages 165-178
  4. Towards Bioeconomy: Potential of Fungal Biotechnology

    1. Front Matter
      Pages 237-237
    2. Maya Benami, Yochai Isack, Dan Grotsky, Danny Levy, Yossi Kofman
      Pages 239-279
  5. Branching Out: Emerging Opportunities

    1. Front Matter
      Pages 315-315
    2. Erin L. Bredeweg, Scott E. Baker
      Pages 317-332
    3. Paola Cicatiello, Ilaria Sorrentino, Alessandra Piscitelli, Paola Giardina
      Pages 333-347
    4. Victoria L. Korn, Sally Padhi, Joan W. Bennett
      Pages 349-368
    5. Martin Hofrichter, Harald Kellner, Robert Herzog, Alexander Karich, Christiane Liers, Katrin Scheibner et al.
      Pages 369-403
    6. Miia R. Mäkelä, Kristiina Hildén, Joanna E. Kowalczyk, Annele Hatakka
      Pages 405-438

About this book


This volume provides a comprehensive overview of the major applications and potential of fungal biotechnology. The respective chapters report on the latest advances and opportunities in each topic area, proposing new and sustainable solutions to some of the major challenges faced by modern society. Aimed at researchers and biotechnologists in academia and industry, it represents essential reading for anyone interested in fungal biotechnology, as well as those working within the broader area of microbial biotechnology. Written in an accessible language, the book also offers a valuable reference resource for decision-makers in government and at non-governmental organizations who are involved in the development of cleaner technologies and the global bioeconomy.

The 21st century is characterized by a number of critical challenges in terms of human health, developing a sustainable bioeconomy, facilitating agricultural production, and establishing practices that support a cleaner environment. While there are chemical solutions to some of these challenges, developing bio-based approaches is becoming increasingly important.

Filamentous fungi, ‘the forgotten kingdom,’ are a group of unique organisms whose full potential has yet to be revealed. Some key properties, such as their exceptional capacity to secrete proteins into the external environment, have already been successfully harnessed for the production of industrial enzymes and cellulosic biofuels. Many further aspects discussed here –such as feeding the hungry with fungal protein, and the potential applications of the various small molecules produced by fungi –warrant further exploration.

In turn, the book covers the use of fungal cell factories to produce foreign molecules, e.g. for therapeutics. Strategies including molecular approaches to strain improvement, and recent advances in high-throughput technologies, which are key to finding better products and producers, are also addressed. Lastly, the book discusses the advent of synthetic biology, which is destined to greatly expand the scope of fungal biotechnology.

The chapter “Fungal Biotechnology in Space: Why and How?” is available open access under a Creative Commons Attribution 4.0 International License at


industrial biotechnology applied microbiology enzyme technology filamentous fungi metabolic engineering

Editors and affiliations

  • Helena Nevalainen
    • 1
  1. 1.Department of Molecular SciencesMacquarie UniversitySydneyAustralia

About the editors

Professor Helena Nevalainen is one of the pioneers in Fungal Biotechnology and has published widely on the topic. She has worked both in industry and academia in Finland and Australia, which has provided her a unique view of Fungal Biotechnology and challenges in the field globally. She has extensive experience from a number of Biotechnology Program steering committees and as an expert consultant to industry. She is currently Professor of Biotechnology at Macquarie University in Australia where she has acted as Director of Masters in Biotechnology Program and graduated several postgraduate students who have since moved on to leading positions nationally and internationally. She has active collaborations with several distinguished scientists and has also acted as an editor and guest editor in Fungal Biotechnology book series and specialist journals.

Bibliographic information

  • Book Title Grand Challenges in Fungal Biotechnology
  • Editors Helena Nevalainen
  • Series Title Grand Challenges in Biology and Biotechnology
  • Series Abbreviated Title Grand Challenges in Biology and Biotechnology
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-030-29540-0
  • Softcover ISBN 978-3-030-29543-1
  • eBook ISBN 978-3-030-29541-7
  • Series ISSN 2367-1017
  • Series E-ISSN 2367-1025
  • Edition Number 1
  • Number of Pages IX, 535
  • Number of Illustrations 26 b/w illustrations, 63 illustrations in colour
  • Topics Microbial Genetics and Genomics
    Applied Microbiology
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