Glioma Imaging

Physiologic, Metabolic, and Molecular Approaches

  • Whitney B. Pope

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Philipp Kickingereder, Ji Eun Park, Jerrold L. Boxerman
    Pages 61-91
  3. Michael Cardenas, Craig J. Galban, Thomas L. Chenevert, Michelle Miller-Thomas, Brian D. Ross, Christina Tsien
    Pages 109-126
  4. Derek R. Johnson, Caterina Giannini, Timothy J. Kaufmann
    Pages 127-138
  5. Melanie A. Morrison, Adam D. Waldman
    Pages 139-159
  6. Ovidiu C. Andronesi, Tracy T. Batchelor, Daniel P. Cahill
    Pages 173-189
  7. Pavithra Viswanath, Yan Li, Sabrina M. Ronen
    Pages 191-209
  8. Norbert Galldiks, Philipp Lohmann, Francesco Cicone, Karl-Josef Langen
    Pages 211-221
  9. Cymon N. Kersch, Ramon F. Barajas Jr.
    Pages 223-239
  10. Julie Ferris, Peter D. Chang, Daniel S. Chow
    Pages 241-249
  11. Elise Wang, Robert J. Young, Ankush Bhatia
    Pages 251-265
  12. Back Matter
    Pages 283-286

About this book


This book covers physiologic, metabolic and molecular imaging for gliomas. Gliomas are the most common primary brain tumors.  Imaging is critical for glioma management because of its ability to noninvasively define the anatomic location and extent of disease. While conventional MRI is used to guide current treatments, multiple studies suggest molecular features of gliomas may be identified with noninvasive imaging, including physiologic MRI and amino acid positron emission tomography (PET). These advanced imaging techniques have the promise to help elucidate underlying tumor biology and provide important information that could be integrated into routine clinical practice.

The text outlines current clinical practice including common scenarios in which imaging interpretation impacts patient management.  Gaps in knowledge and potential areas of advancement based on the application of more experimental imaging techniques will be discussed. In reviewing this book, readers will learn: 

  • current standard imaging methodologies used in clinical practice for patients undergoing treatment for glioma and the implications of emerging treatment modalities including immunotherapy
  • the theoretical basis for advanced imaging techniques including diffusion and perfusion MRI, MR spectroscopy, CEST and amino acid PET 
  • the relationship between imaging and molecular/genomic glioma features incorporated in the WHO 2016 classification update and the potential application of machine learning
  • about  the recently adopted and FDA approved standard brain tumor protocol for multicenter drug trials
  • of the gaps in knowledge that impede optimal patient management and the cutting edge imaging techniques that could address these deficits


glioma brain tumor neuroimaging low grade glioma radiogenomics metabolic imaging

Editors and affiliations

  • Whitney B. Pope
    • 1
  1. 1.David Geffen School of Medicine at UCLALos AngelesUSA

Bibliographic information