OCT and Imaging in Central Nervous System Diseases

The Eye as a Window to the Brain

  • Andrzej Grzybowski
  • Piero Barboni

Table of contents

  1. Front Matter
    Pages i-x
  2. Andrzej Grzybowski, Piero Barboni
    Pages 1-5
  3. Tigran Kostanyan, Maria de los Angeles Ramos-Cadena, Gadi Wollstein, Joel S. Schuman
    Pages 7-31
  4. Aykut Aytulun, Andrés Cruz-Herranz, Lisanne Balk, Alexander U. Brandt, Philipp Albrecht
    Pages 33-39
  5. Enrico Borrelli, Srinivas R. Sadda, Akihito Uji, Giuseppe Querques
    Pages 41-54
  6. Delia Cabrera DeBuc, Gábor Márk Somfai, Gabriella Szatmáry, Edmund Arthur, Jorge A. Jimenez, Carlos Mendoza-Santiesteban et al.
    Pages 55-82
  7. Maya Koronyo-Hamaoui, Jonah Doustar, Mia Oviatt, Keith L. Black, Yosef Koronyo
    Pages 83-122
  8. Timothy E. Yap, Maja Szymanska, M. Francesca Cordeiro
    Pages 123-138
  9. Anna Bryndis Einarsdottir, Olof Birna Olafsdottir, Sveinn Hakon Hardarson
    Pages 139-145
  10. Laurel N. Vuong, Thomas R. Hedges III
    Pages 147-167
  11. Mário Luiz Ribeiro Monteiro
    Pages 169-194
  12. James V. M. Hanson, Carla A. Wicki, Praveena Manogaran, Axel Petzold, Sven Schippling
    Pages 195-233
  13. Ivan Bodis-Wollner, Shahnaz Miri, Sofya Glazman, Eric M. Shrier, Reem Deeb
    Pages 235-262
  14. Gianluca Coppola, Vincenzo Parisi, Gianluca Manni, Francesco Pierelli, Alfredo A. Sadun
    Pages 263-288
  15. Francisco J. Ascaso, Javier Mateo, Laura Cabezón, Paula Casas, Andrzej Grzybowski
    Pages 317-342
  16. Piero Barboni, Nicole Balducci, Alfredo A. Sadun
    Pages 343-364
  17. Bernardo F. Sánchez-Dalmau, Anna Camós-Carreras, Ruben Torres-Torres, Johannes Keller, Laura Sanchez-Vela, Elena H. Martínez-Lapiscina et al.
    Pages 365-374
  18. Andrzej Grzybowski, Iwona Obuchowska, Carl Arndt
    Pages 375-400
  19. Eduardo M. Normando, M. Francesca Cordeiro
    Pages 401-426
  20. Harsha Rao, Kaweh Mansouri, Robert Weinreb
    Pages 427-472
  21. Paolo Nucci, Andrea Lembo, Stefano Lucentini, Francesco Pichi
    Pages 473-485
  22. Maja Kostic, Gábor Márk Somfai, Edmund Arthur, Delia Cabrera DeBuc
    Pages 487-505
  23. Rui Bernardes, Lília Jorge, Ana Nunes, Miguel Castelo-Branco
    Pages 507-521
  24. Alexander Pinhas, Valerie I. Elmalem, Maria Castanos Toral, Davis B. Zhou, Jorge S. Andrade Romo, Alexander Barash et al.
    Pages 523-544
  25. Back Matter
    Pages 549-561

About this book


The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models.

Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.


Neurodegenerative Diseases Optic Neuropathy Optical Coherence Topography Retinal Nerve Fiber Layer Neuro-Ophthalmology Imaging

Editors and affiliations

  • Andrzej Grzybowski
    • 1
  • Piero Barboni
    • 2
  1. 1.University of Warmia and MazuryOlsztynPoland
  2. 2.Studio Oculistico d’AzeglioBolognaItaly

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-030-26268-6
  • Online ISBN 978-3-030-26269-3
  • Buy this book on publisher's site