Heart of the Matter

Key concepts in cardiovascular science

  • Cesare Terracciano
  • Samuel Guymer

Part of the Learning Materials in Biosciences book series (LMB)

Table of contents

  1. Front Matter
    Pages I-XV
  2. Dominic Gyimah, Alec Saunders, Elizabeth Thong, Balvinder Handa
    Pages 1-11
  3. Jack Griffiths, Thomas Brand
    Pages 13-23
  4. Beth Taylor, Thomas Brand
    Pages 25-37
  5. Umamah Tarvala, Zohya Khalique
    Pages 39-48
  6. Elizabeth Thong, Ayesha Ahmed, Kenneth T. MacLeod
    Pages 49-59
  7. Fotios G. Pitoulis, Cesare M. Terracciano
    Pages 61-75
  8. Alec Saunders, Fu Siong Ng
    Pages 77-85
  9. Rohin K. Reddy, Ben N. Cullen, Ahran D. Arnold, Zachary I. Whinnett
    Pages 87-103
  10. Dominic Gyimah, Ahran D. Arnold, Zachary I. Whinnett
    Pages 105-119
  11. Fotios G. Pitoulis, Pieter P. de Tombe
    Pages 121-133
  12. Giles Chick, Fotios G. Pitoulis, Liam Couch
    Pages 135-144
  13. Praveena Krishnakumar, Kabir Matwala, Shiv-Raj Sharma, Salomon Narodden
    Pages 145-153
  14. Angeliki Iakovou, Samuel Guymer, Rasheda Chowdhury
    Pages 155-166
  15. Haaris Rahim, Yasmin Bashir, Michael Schachter
    Pages 179-191
  16. Lieze Thielemans, Moghees Hanif, James Crawley
    Pages 193-206
  17. Adam Tsao, Mridul Rana, Joseph J. Boyle
    Pages 207-218
  18. Zarius Ferozepurwalla, Jude Merzah, Lieze Thielemans, Graeme Birdsey
    Pages 219-226
  19. Mridul Rana, Zarius Ferozepurwalla, Justin Mason
    Pages 227-236

About this book


This textbook introduces readers to the scientific basics of cardiovascular medicine and biology. It covers not only developmental but also cellular and molecular aspects of normally functioning vasculature and the heart; importantly, it also addresses the mechanisms leading to and involved in specific cardiovascular diseases. Though the main emphasis is on novel therapies and potential therapeutic targets, specific controversial topics like cardiac remodeling and regenerative capacities are also addressed.

All chapters were written by lecturers from the Imperial College London, in collaboration with their students from the College’s BSc Programme in Medical Sciences with Cardiovascular Science. Bridging the gap between clinics and basic biology, the book offers a valuable guide for medical students, and for Master and PhD students in Cardiovascular Biomedicine.


Angiogenesis Arrhythmia Atherosclerosis Calcium Signalling in the Heart Cardiomyocyte Cardiac Action Potentials Cardiac Development Cardiovascular Embryonic Development Cardiac Morphology Cardiac 3D Printing Coagulation Cascade Comparative Developmental Anatomy Congenital Heart Disease Cardiac Regenerative Capacity Coronary Vasculature Early Mechanisms of Cardiac Development Endothelial Function Therapeutics for Cardiovascular Disease Translational Cardiology

Editors and affiliations

  • Cesare Terracciano
    • 1
  • Samuel Guymer
    • 2
  1. 1.National Heart & Lung InstituteImperial College LondonLondonUK
  2. 2.Imperial College London & St George’s Medical SchoolLondonUK

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-030-24218-3
  • Online ISBN 978-3-030-24219-0
  • Series Print ISSN 2509-6125
  • Series Online ISSN 2509-6133
  • Buy this book on publisher's site