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Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics

  • Erika Ruiz-Garcia
  • Horacio Astudillo-de la Vega
Book

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1168)

Table of contents

  1. Front Matter
    Pages i-x
  2. Edith A. Fernández-Figueroa, Saul Lino-Silva, Jorge E. Peña-Velasco, Claudia Rangel-Escareño
    Pages 1-7
  3. Stefania Morganti, Paolo Tarantino, Emanuela Ferraro, Paolo D’Amico, Bruno Achutti Duso, Giuseppe Curigliano
    Pages 9-30
  4. César López-Camarillo, Dolores Gallardo-Rincón, María Elizbeth Álvarez-Sánchez, Laurence A. Marchat
    Pages 31-42
  5. María Luisa Romero Lagunes, Francisco Emilio Vera Badillo
    Pages 43-77
  6. Juan-Manuel Hernandez-Martinez, Roberto Sánchez-Reyes, J. G. De la Garza-Salazar, Oscar Arrieta
    Pages 79-90
  7. Rohan P. Joshi, David F. Steiner, Eric Q. Konnick, Carlos J. Suarez
    Pages 103-115
  8. William R. Gwin III, Mary L. Disis, Erika Ruiz-Garcia
    Pages 117-129
  9. Marlid Cruz-Ramos, Jesús García-Foncillas
    Pages 131-145
  10. H. Astudillo-de la Vega, O. Alonso-Luna, J. Ali-Pérez, C. López-Camarillo, E. Ruiz-Garcia
    Pages 147-156
  11. Jóse Ali Flores-Pérez, Fabiola de la Rosa Oliva, Yacab Argenes, Abelardo Meneses-Garcia
    Pages 157-168
  12. Back Matter
    Pages 169-171

About this book

Introduction

This book presents concise chapters written by internationally respected experts on various important aspects of translational cancer genomics, offering a comprehensive overview of the onco-omics applications in the new era of cancer personal genomics research field. Being a complex disease that affects millions of people worldwide, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. In the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and even more, considering the immune system, the metabolism and in the near future the microbiome, all areas nowadays related in the prognosis and treatment of cancer patients. These contributions are either critical reviews or clinical and basic research reports. The topics discussed here include evidence-based medicine and provides useful information on translational cancer research to clinicians and biomedical scientists in order to offer another vision of cancer origin beyond the traditional causes or the oncogenic maintenance concept proposed by the oncogene addiction theory.

Keywords

OMICS Cancer Pharmacogenomics Personalized Medicine CAR T-cell

Editors and affiliations

  • Erika Ruiz-Garcia
    • 1
  • Horacio Astudillo-de la Vega
    • 2
  1. 1.Department of Gastrointestinal Medical Oncology & Translational Medicine LaboratoryInstituto Nacional de CancerologiaMexico CityMexico
  2. 2.Translational Research Laboratory in Cancer & Celullar TherapyHospital de Oncologia, Siglo XXI, IMSSMexico CityMexico

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-030-24100-1
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-030-24099-8
  • Online ISBN 978-3-030-24100-1
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site