© 2019

Precision Cancer Medicine

Challenges and Opportunities

  • Sameek Roychowdhury
  • Eliezer M. Van Allen

Table of contents

  1. Front Matter
    Pages i-vi
  2. Sameek Roychowdhury, Eliezer M. Van Allen
    Pages 1-3
  3. Nathanael D. Moore, Parastou Ghazi, Eliezer M. Van Allen
    Pages 33-48
  4. Senthil Damodaran, Jason Willis, Sameek Roychowdhury
    Pages 49-63
  5. Jennifer A. Woyach
    Pages 65-82
  6. Michael Cheng, Gopa Iyer
    Pages 83-97
  7. Jonathan J. Havel, Alexandra Snyder
    Pages 99-110
  8. Jessica N. Everett, Victoria M. Raymond
    Pages 111-128
  9. J. Scott Roberts, Michele R. Gornick
    Pages 129-143
  10. Daniel Zainfeld, Umair Ghani, Irene Kang, Amir Goldkorn
    Pages 145-167
  11. Angelica Ochoa, Nikolaus Schultz
    Pages 169-196

About this book


This comprehensive book was written by leading researchers in the emerging and changing field of precision cancer medicine. Precision cancer medicine entails connecting the right molecular diagnosis to the right treatment plan for individual patients. The textbook covers a range of topics from basic science to clinical application for patient care. Precision cancer medicine includes multi-disciplinary fields of research expertise ranging from genomics, pathology, oncology, hereditary genetics, bioinformatics, immunology, cancer biology, and bioethics.

Basic topics include molecular diagnostics, liquid biopsy, immunogenomics, drug resistance mechanisms, and bioinformatics analyses of big data. The clinical topics include clinical interpretation, hereditary cancers, designs of basket clinical trials, exceptional responders, and the ethical, legal, and social implications of clinical genomics research.

Readers who are involved in one of the specialities of precision cancer medicine can benefit from this book through exposure to other fields. Any level of training or professional practice can benefit from the broad exposure this book can provide.




Precision Cancer Medicine Pediatric oncology Germline genetics Molecular pathology Immunogenomics

Editors and affiliations

  • Sameek Roychowdhury
    • 1
  • Eliezer M. Van Allen
    • 2
  1. 1.Department of Internal MedicineDivision of Medical Oncology Comprehensive Cancer Center & The Arthur G. James Cancer Hospital at The Ohio State UniversityColumbusUSA
  2. 2.Dana-Farber Cancer InstituteBostonUSA

About the editors

Dr. Roychowdhury is a physician scientist in medical oncology focusing on translational cancer genomics and implementing precision cancer medicine. His clinical practice in medical oncology includes patients with advanced, metastatic cancer including prostate, colorectal, and rare cancer subtypes.

Bibliographic information

  • Book Title Precision Cancer Medicine
  • Book Subtitle Challenges and Opportunities
  • Editors Sameek Roychowdhury
    Eliezer M. Van Allen
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-3-030-23636-6
  • Softcover ISBN 978-3-030-23639-7
  • eBook ISBN 978-3-030-23637-3
  • Edition Number 1
  • Number of Pages VI, 196
  • Number of Illustrations 2 b/w illustrations, 31 illustrations in colour
  • Topics Cancer Research
  • Buy this book on publisher's site