Human Cell Transformation

Advances in Cell Models for the Study of Cancer and Aging

  • Johng S. Rhim
  • Anatoly Dritschilo
  • Richard Kremer

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1164)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Mechanisms of Tumor Progression

    1. Front Matter
      Pages 1-1
    2. Jason R. Pitarresi, Anil K. Rustgi
      Pages 3-10
    3. Hui Mei Lee, Kazuhida Shaun Okuda, Fermín E. González, Vyomesh Patel
      Pages 11-34
    4. Jun Fujita, Toshiharu Sakurai
      Pages 63-71
    5. Byoung-Joon Song, Mohamed A. Abdelmegeed, Young-Eun Cho, Mohammed Akbar, Johng S. Rhim, Min-Kyung Song et al.
      Pages 73-87
  3. Prostate Cancer Progression

    1. Front Matter
      Pages 89-89
    2. Nicole Nicolas, Geeta Upadhyay, Alfredo Velena, Bhaskar Kallakury, Johng S. Rhim, Anatoly Dritschilo et al.
      Pages 101-108
    3. Fiona M. Frame, Amanda R. Noble, Peter O’Toole, Jo Marrison, Timothy Godden, Andrew O’Brien et al.
      Pages 109-118
    4. Amrita K. Cheema, Scott Grindrod, Xiaogang Zhong, Shreyans Jain, Smrithi S. Menon, Khyati Y. Mehta et al.
      Pages 141-150
  4. Skeletal Dysregulation and Cancer Spread to the Skeleton

    1. Front Matter
      Pages 151-151
    2. David Goltzman
      Pages 153-160
    3. Rui Zhang, Jiarong Li, Gloria Assaker, Anne Camirand, Siham Sabri, Andrew C. Karaplis et al.
      Pages 161-178
    4. Niaz Mahmood, Shafaat A. Rabbani
      Pages 179-196
  5. Targeting the Tumor and Its Microenvironment

    1. Front Matter
      Pages 197-197
    2. John E. Davis Jr, Jason Kirk, Yibing Ji, Dean G. Tang
      Pages 199-206
    3. Norman J. Maitland, Fiona M. Frame, Jayant K. Rane, Holger H. Erb, John R. Packer, Leanne K. Archer et al.
      Pages 207-224
  6. Back Matter
    Pages 235-244

About this book


This book, part contributed volume, part proceedings, discusses state-of-the-art advances on human cell transformation in cell models for the study of cancer and aging. Several of the chapters are from the Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging conference that was held in June 2018 at McGill University. The authors represent international expertise on a wide variety of topics ranging from different types of cancer (prostate, bone, breast, etc.) to tumor microenvironment, tumor progression, homogeneity, and possible therapies and treatments.


cancer cell cancer and aging cell transformation cancer immunotherapy heterogeneity

Editors and affiliations

  • Johng S. Rhim
    • 1
  • Anatoly Dritschilo
    • 2
  • Richard Kremer
    • 3
  1. 1.Department of SurgeryUniformed Services University of the Health SciencesBethesdaUSA
  2. 2.Georgetown University Medical CenterWashington, DCUSA
  3. 3.Department of MedicineMcGill University Health CentreMontréalCanada

Bibliographic information