Clinical and Surgical Management

  • Sabine Sarnacki
  • Luca Pio

Table of contents

  1. Front Matter
    Pages i-viii
  2. Epidemiology, Biology and Pathology Assessment

    1. Front Matter
      Pages 1-1
    2. Jacqueline Clavel, Brigitte Lacour, Paula Rios
      Pages 3-15
    3. Gudrun Schleiermacher
      Pages 17-28
    4. Isabelle Janoueix-Lerosey
      Pages 29-56
    5. Hiroyuki Shimada, Angela R. Sementa, Bruce R. Pawel, Naohiko Ikegaki
      Pages 57-83
  3. Imaging

    1. Front Matter
      Pages 85-85
    2. Hervé J. Brisse, Martijn Verhagen, Kieran McHugh, Claudio Granata
      Pages 87-117
    3. Giovanni Cecchetto, Tom Monclair, Hervé J. Brisse
      Pages 119-137
    4. Arnoldo Piccardo, Rita Castellani, Gianluca Bottoni, Michela Massollo, Giulia Anna Follacchio, Egesta Lopci
      Pages 139-162
    5. Tom Boterberg
      Pages 163-170
  4. Clinical Management

    1. Front Matter
      Pages 171-171
    2. Shifra Ash, Stefania Sorrentino, Kathelijne Kraal, Bruno De Bernardi
      Pages 173-189
    3. Dominique Plantaz, Claire Freycon
      Pages 191-203
    4. Vanessa Segura, Adela Cañete
      Pages 205-212
    5. Katherine K. Matthay, Dominique Valteau-Couanet
      Pages 213-235
    6. Francesca del Bufalo, Franco Locatelli
      Pages 237-269
    7. Meredith S. Irwin
      Pages 271-292
  5. Surgery

    1. Front Matter
      Pages 293-293
    2. Dhanya Mullassery, Laurence Abernethy, Rajeev Shukla, Paul D. Losty
      Pages 295-311
    3. James A. Saltsman III, Nicole J. Croteau, Michael P. LaQuaglia
      Pages 313-325
    4. Sanjeev A. Vasudevan, Jed G. Nuchtern
      Pages 327-336
    5. Luca Pio, Thomas Blanc, Christophe Glorion, Stephanie Puget, Michel Zerah, Sabine Sarnacki
      Pages 337-342
    6. Jörg Fuchs, Steven W. Warmann
      Pages 343-355
    7. Luca Pio, Thomas Blanc, Girolamo Mattioli, Yves Heloury, Sabine Sarnacki
      Pages 357-362
    8. Alessandro Inserra, Alessandro Crocoli
      Pages 375-383

About this book


This book addresses neuroblastoma, a type of embryonic tumor derived from neural crest cells and one of the most frequent extra-cranial solid tumors in children. However, the term also describes a heterogeneous group of tumors, the prognosis of which can differ greatly according to age, stage and biology. Some forms undergo spontaneous regression, and some are cured by surgery alone or after chemo-reduction, while others exhibit extremely aggressive behavior. Their successful treatment is one of the best examples of tailored medicine, which involves close collaboration between pediatric surgeons, pediatric oncologists, radiologists, nuclear medicine specialists, biologists, oncogeneticists and radiotherapists.   

The book pursues a unique approach, as it combines most essential insights from all of these fields, together with key information regarding epidemiology, physiopathology and palliative care. The respective chapters were written by the leading international experts on neuroblastoma, and present the latest advances in terms of research, surgical approaches and medical treatments. The book offers an invaluable resource to all pediatric surgeons, pediatricians, oncologists, students, researchers and all others involved in neuroblastoma management who want to benefit from their colleagues’ expertise.


pediatric surgery pediatric oncology surgical oncology clinical oncology spinal canal involvement immunotherapy

Editors and affiliations

  • Sabine Sarnacki
    • 1
  • Luca Pio
    • 2
  1. 1.Department of Pediatric Surgery, Necker - Enfants Malades Hospital, Assistance Publique Hopitaux de ParisUniversity of ParisParisFrance
  2. 2.Department of Pediatric Surgery, Necker - Enfants Malades Hospital, Assistance Publique Hopitaux de ParisUniversity of ParisParisFrance

Bibliographic information