Extracellular Sugar-Based Biopolymers Matrices

  • Ephraim Cohen
  • Hans Merzendorfer

Part of the Biologically-Inspired Systems book series (BISY, volume 12)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Aminosugar-Based Exopolysaccharides: Chitin-Based Extracellular Matrices

    1. Front Matter
      Pages 1-1
    2. Xiaoming Zhao, Jianzhen Zhang, Kun Yan Zhu
      Pages 3-56
    3. Ingrid M. Weiss
      Pages 57-93
  3. Aminosugar-Based Exopolysaccharides: Glucosaminoglycans

    1. Front Matter
      Pages 153-153
    2. Alberto Passi, Davide Vigetti
      Pages 155-186
    3. Emiliano Bedini, Maria Michela Corsaro, Alfonso Fernández-Mayoralas, Alfonso Iadonisi
      Pages 187-233
  4. Aminosugar-Based Exopolysaccharides: Peptidoglycans

    1. Front Matter
      Pages 235-235
  5. Glucose-Based Exopolysaccharides

    1. Front Matter
      Pages 301-301
    2. Xiaoyu Zhu, Xiaoran Xin, Ying Gu
      Pages 303-353
    3. Diego O. Serra, Regine Hengge
      Pages 355-392
    4. Daniel Prieto, Elvira Román, Rebeca Alonso-Monge, Jesús Pla
      Pages 393-407
    5. Mario A. A. Cunha, Vidiany A. Q. Santos, Gabrielle C. Calegari, William N. Sánchez Luna, Sandra L. A. Marin, Robert F. H. Dekker et al.
      Pages 409-432
    6. Robert F. H. Dekker, Eveline A. I. F. Queiroz, Mario A. A. Cunha, Aneli M. Barbosa-Dekker
      Pages 433-484
  6. Galacturonic Acid and Xylolactan-Based Exopolysaccharide

    1. Front Matter
      Pages 485-485
  7. Alginic Acid-Based Exopolysaccharides

    1. Front Matter
      Pages 515-515
    2. M. Fata Moradali, Bernd H. A. Rehm
      Pages 517-537
  8. Industrial and Biomedical Applications of Biopolysaccharides

    1. Front Matter
      Pages 539-539
    2. Patrícia Sofia Pinhanços Batista, Alcina Maria Miranda Bernardo de Morais, Maria Manuela Estevez Pintado, Rui Manuel Santos Costa de Morais
      Pages 649-691
    3. Oded Shoseyov, Doron Kam, Tal Ben Shalom, Zvi Shtein, Sapir Vinkler, Yehudit Posen
      Pages 693-784
  9. Back Matter
    Pages 785-820

About this book


The extracellular matrix (ECM) is an acellular three-dimensional network composed of proteins, glycoproteins, proteoglycans and exopolysaccharides. It primarily serves as a structural component in the tissues and organs of plants and animals, or forms biofilms in which bacterial cells are embedded. ECMs are highly dynamic structures that undergo continuous remodeling, and disruptions are frequently the result of pathological processes associated with severe diseases such as arteriosclerosis, neurodegenerative illness or cancer. In turn, bacterial biofilms are a source of concern for human health, as they are associated with resistance to antibiotics. Although exopolysaccharides are crucial for ECM formation and function, they have received considerably little attention to date.

The respective chapters of this book comprehensively address such issues, and provide reviews on the structural, biochemical, molecular and biophysical properties of exopolysaccharides. These components are abundantly produced by virtually all taxa including bacteria, algae, plants, fungi, invertebrates and vertebrates. They include long unbranched homopolymers (cellulose, chitin/chitosan), linear copolymers (alginate, agarose), peptoglycans such as murein, heteropolymers like a variety of glycosaminoglycans (hyaluronan, dermatan, keratin, heparin, Pel), and branched heteropolymers such as pectin and hemicellulose.

A separate chapter is dedicated to modern industrial and biomedical applications of exopolysaccharides and polysaccharide-based biocomposites. Their unique chemical, physical and mechanical properties have attracted considerable interest, inspired basic and applied research, and have already been harnessed to form structural biocomposite hybrids for tailor-made applications in regenerative medicine, bioengineering and biosensor design.

Given its scope, this book provides a substantial source of basic and applied information for a wide range of scientists, as well as valuable textbook for graduate and advanced undergraduate students.


Extracellular matrices Extracellular polysaccharides Bacterial biofilms Industrial and biomedical applications Animal biochemistry Plant Biochemistry

Editors and affiliations

  • Ephraim Cohen
    • 1
  • Hans Merzendorfer
    • 2
  1. 1.Department of Entomology, The Robert H. Smith Faculty of Agriculture Food and EnvironmentThe Hebrew University of JerusalemRehovotIsrael
  2. 2.School of Science and Technology, Institute of Biology – Molecular BiologyUniversity of SiegenSiegenGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-030-12918-7
  • Online ISBN 978-3-030-12919-4
  • Series Print ISSN 2211-0593
  • Series Online ISSN 2211-0607
  • Buy this book on publisher's site