Nijkamp and Parnham's Principles of Immunopharmacology

  • Michael J. Parnham
  • Frans P. Nijkamp
  • Adriano G. Rossi

Table of contents

  1. Front Matter
    Pages i-xxviii
  2. Michael J. Parnham, Frans P. Nijkamp, Adriano G. Rossi
    Pages 1-6
  3. Immunity

    1. Front Matter
      Pages 7-7
    2. Menno C. van Zelm, Magdalena B. Rother, Frank J. T. Staal
      Pages 9-21
    3. Femke Broere, Willem van Eden
      Pages 23-35
    4. Ger T. Rijkers, Bob Meek
      Pages 37-53
    5. Christina Dillmann, Geert R. Van Pottelberge, Ken R. Bracke, Guy G. Brusselle
      Pages 55-68
    6. Bastian Schirmer, Detlef Neumann
      Pages 69-91
    7. Shahzad N. Syed, Eduard Resch, Nathalie Dehne
      Pages 93-116
    8. Michael J. Parnham, Adriano G. Rossi
      Pages 117-137
    9. Richard Korbut, Tomasz J. Guzik
      Pages 139-163
    10. Javier Mora, Warner Alpízar-Alpízar, Andreas Weigert
      Pages 191-208
    11. Natalia P. Rocha, Moises E. Bauer, Antonio L. Teixeira
      Pages 209-230
  4. Immunodiagnosis

    1. Front Matter
      Pages 231-231
    2. Frank Redegeld, Klaus Hermann, Markus Ollert, Johannes Ring
      Pages 233-241
    3. Martin Schwickart, Inna Vainshtein
      Pages 243-253
    4. John F. Dunne, Holden T. Maecker
      Pages 255-270
    5. Julia Tree, Angela Essex-Lopresti, Stefan Wild, Ute Bissels, Barbara Schaffrath, Andreas Bosio et al.
      Pages 271-290
    6. Thomas H. Craven, Philippe M. D. Potey, David A. Dorward, Adriano G. Rossi
      Pages 291-308
  5. Immunotherapeutics

    1. Front Matter
      Pages 309-309
    2. Gideon F. A. Kersten, Wim Jiskoot
      Pages 311-326
    3. Adrian W. Zuercher, Mel Berger, Reinhard Bolli, Cédric Vonarburg, Martin Spycher, Amgad Shebl et al.
      Pages 327-368
    4. Frank R. Brennan, Emma Smith, Sherri Dudal
      Pages 369-406
    5. Eva M. Valesky, Sue McKay, Antoon J. M. van Oosterhout, Michael J. Parnham
      Pages 407-423
    6. Gaetano Caramori, Ian M. Adcock, Peter J. Barnes, Kian Fan Chung
      Pages 425-474
    7. James E. Talmadge
      Pages 491-531
    8. Evangelos J. Giamarellos-Bourboulis
      Pages 533-544
    9. Prescilla V. Jeurink, Negisa Seyed Toutounchi, Hamed Janbaz Acyabar, Gert Folkerts, Johan Garssen
      Pages 545-559
    10. Michael J. Parnham, Višnja Stepanić, Nadja Tafferner, Marina Panek, Donatella Verbanac
      Pages 561-587
    11. Martina Bosnar, Vesna Eraković Haber, Garry G. Graham
      Pages 589-611
    12. Sabine Grösch, Guido Bocci, Antonello Di Paolo, Romano Danesi
      Pages 613-627
    13. Henk-Jan Schuurman
      Pages 629-660
    14. Gaetano Caramori, Sharon Mumby, Giuseppe Girbino, Kian Fan Chung, Ian M. Adcock
      Pages 661-688
    15. Eeva Moilanen, Katriina Vuolteenaho
      Pages 689-707
    16. Kevin D. Pile, Garry G. Graham, Stephen M. Mahler, Richard O. Day
      Pages 709-750
    17. Carolin F. Manthey, Marcial Sebode, Helen Hayward-Koennecke, Andreas Lutterotti, Samuel Huber
      Pages 751-775
    18. Christina Wiedl, Kamar Godder
      Pages 777-783
  6. Immunotoxicology

    1. Front Matter
      Pages 785-785
    2. Raymond Pieters, Jan Willem van der Laan, Henk van Loveren
      Pages 787-818
  7. Back Matter
    Pages 819-888

About this book


Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The 4th edition of this internationally recognized textbook has been revised to include recent developments, but continues the established format, dealing with four related fields in a single volume, thus obviating the need to refer to several different textbooks.

The first section of the book, providing a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts, particularly the role of epigenetics and the latest understanding of cancer immunology. The second section on immunodiagnostics offers a topical description of widely used molecular techniques and a new chapter on imaging techniques. This is followed by a systematic coverage of drugs affecting the immune system, including natural products. This third section contains 15 updated chapters, covering classical immunopharmacological topics such as anti-asthmatic, anti-rheumatic and immunosuppressive drugs, but also deals with antibiotics, plant-derived and dietary agents, with new chapters on monoclonal antibodies, immunotherapy in sepsis and infection, drugs for soft-tissue autoimmunity and cell therapy. The book concludes with a chapter on immunotoxicology and drug safety tests.

Aids to the reader include a two-column format, glossaries of technical terms and appendix reference tables. The emphasis on illustrations is maintained from the first three editions.

The book is a valuable single reference for undergraduate and graduate medical and biomedical students, postgraduate chemistry and pharmacy students, researchers in chemistry, biochemistry and the pharmaceutical industry and researchers lacking basic immunological knowledge, who want to understand the actions of drugs on the immune system.


Immunity Immunodiagnosis Immunotherapeutics Immunotoxicology Pharmacology

Editors and affiliations

  • Michael J. Parnham
    • 1
  • Frans P. Nijkamp
    • 2
  • Adriano G. Rossi
    • 3
  1. 1.Translational Drug Validation, Fraunhofer IME-TMP and Goethe University FrankfurtFrankfurt am MainGermany
  2. 2.Utrecht UniversityUtrechtThe Netherlands
  3. 3.The Queen’s Medical Research Institute, MRC Centre for Inflammation ResearchUniversity of EdinburghEdinburghUK

Bibliographic information