Gender and Migraine

  • Antoinette Maassen van den Brink
  • E. Anne MacGregor

Part of the Headache book series (HEAD)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Kjersti Grøtta Vetvik
    Pages 1-15
  3. L. Al-Hassany, K. A. Linstra, G. M. Terwindt, Antoinette Maassen van den Brink
    Pages 17-29
  4. Daphne S. van Casteren, Emile G. M. Couturier, Antoinette Maassen van den Brink
    Pages 31-43
  5. Andrea Negro, Dimos Dimitrios Mitsikostas
    Pages 45-68
  6. Francesca Pistoia, Simona Sacco
    Pages 69-79
  7. Gabriele S. Merki-Feld
    Pages 81-88
  8. Eloísa Rubio-Beltrán, Alejandro Labastida-Ramírez
    Pages 89-100
  9. E. Anne MacGregor, Antoinette Maassen van den Brink
    Pages 113-127

About this book


This book focuses on the influence of sex and gender in migraine, presenting new insights in basic science as well as their clinical relevance.  As migraine is roughly three times more common in women than in men, and also highly depends on hormonal milestones – such as menarche, menstruation, pregnancy and menopause – particular attention is devoted to the role of female sex hormones in this disease. 

The first chapters present general data on gender-related differences in migraine such as epidemiology, comorbidities and related risks. Furthermore, while several chapters focus on the role of female sex hormones in migraine-triggering mechanisms at a basic scientific level (e.g. cranial circulation), ample attention is also paid to the clinical relevance of such mechanisms and to the best clinical treatment for migraine patients.

As the first book entirely devoted to this topic, it will be of interest to researchers and practitioners in the fields of neurology, internal medicine, endocrinology, physiology and pharmacology.


migraine in women female sex hormones extrogen progesteron menstruation pregnancy transgender hormonal contraception cranial circulation

Editors and affiliations

  • Antoinette Maassen van den Brink
    • 1
  • E. Anne MacGregor
    • 2
  1. 1.Division of Pharmacology and Vascular MedicineErasmus University Medical Center RotterdamRotterdamThe Netherlands
  2. 2.Barts Health NHS TrustLondonUK

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-030-02987-6
  • Online ISBN 978-3-030-02988-3
  • Series Print ISSN 2197-652X
  • Series Online ISSN 2197-6538
  • Buy this book on publisher's site