Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis

  • Renato Alberto Sinico
  • Loïc Guillevin

Part of the Rare Diseases of the Immune System book series (RDIS)

Table of contents

  1. Front Matter
    Pages i-x
  2. ANCA-Associated Vasculitis

    1. Front Matter
      Pages 1-1
    2. J. Charles Jennette, Ronald J. Falk
      Pages 3-17
    3. Federico Alberici, Paul Anthony Lyons, Davide Martorana
      Pages 19-32
    4. Delphine Sterlin, Alexis Mathian, Makoto Miyara
      Pages 33-45
    5. Elena Csernok, Antonella Radice
      Pages 47-56
    6. Raashid A. Luqmani
      Pages 57-76
    7. Christian Pagnoux
      Pages 97-129
    8. Renato Alberto Sinico, Filippo Maria Sala, Maria Rosa Pozzi, Paolo Fabbrini, Federico Pieruzzi
      Pages 131-144
  3. Vasculitis/Organs Involvement

    1. Front Matter
      Pages 145-145
    2. Trimarchi Matteo, Galli Andrea, Roberto Teggi
      Pages 147-161
    3. Marta Casal Moura, Ulrich Specks
      Pages 163-176
    4. Renato Alberto Sinico, Fabio Pagni, Vincenzo L’Imperio, Valentina Binda, Paolo Fabbrini, Federico Pieruzzi et al.
      Pages 177-192
    5. Michael P. Collins, P. James B. Dyck
      Pages 193-237
    6. Angelo Valerio Marzano, Simona Tavecchio, Emilio Berti
      Pages 251-267
    7. Giorgio Trivioli, Augusto Vaglio
      Pages 269-292
    8. Loïc Guillevin, Loïc Raffray, Yann Nguyen, Benjamin Chaigne, Benjamin Terrier
      Pages 313-328
  4. Back Matter
    Pages 329-336

About this book


This volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others.

The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area.

The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. AAVs are systemic autoimmune diseases of unknown cause that affect small (to medium) sized blood vessels. They include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (formerly Churg–Strauss syndrome).

This volume will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these diseases.


Granulomatosis Microscopic Polyangitis Polyangitis Eosinophilic Granulomatosis B Lymphocytes T Lymphocytes Rare Immune Diseases

Editors and affiliations

  • Renato Alberto Sinico
    • 1
  • Loïc Guillevin
    • 2
  1. 1.Department of Medicine and SurgeryUniversity of Milano-BicoccaMonzaItaly
  2. 2.Department of MedicineParis Descartes University Hospital CochinParisFrance

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2020
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-3-030-02238-9
  • Online ISBN 978-3-030-02239-6
  • Series Print ISSN 2282-6505
  • Series Online ISSN 2283-6403
  • Buy this book on publisher's site