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Nanotheranostics for Cancer Applications

  • Prakash Rai
  • Stephanie A. Morris

Part of the Bioanalysis book series (BIOANALYSIS, volume 5)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Introduction to Cancer and Nanotechnology

    1. Front Matter
      Pages 1-1
    2. Praveena Velpurisiva, Janel L. Kydd, Rahul Jadia, Stephanie A. Morris, Prakash Rai
      Pages 3-12
    3. Uma Prabhakar, Yalia Jayalakshmi, C. Katherine Wang
      Pages 33-66
    4. Liang Ma, Phuong Le, Manish Kohli, Andrew M. Smith
      Pages 67-90
  3. Cancer Nanodiagnostics and Nanotherapeutics

    1. Front Matter
      Pages 107-107
    2. Jung-Rok Lee, Chin Chun Ooi, Shan X. Wang
      Pages 109-132
    3. Christina H. Liu, Pushpa Tandon, Luisa M. Russell
      Pages 133-162
    4. Bomy Lee Chung, Joseph Kaplinsky, Robert Langer, Nazila Kamaly
      Pages 163-205
    5. Yanqi Ye, Jinqiang Wang, Wujin Sun, Hunter N. Bomba, Zhen Gu
      Pages 231-251
    6. Kyle C. Roche, Yusra Betul Medik, Zach Rodgers, Sam Warner, Andrew Z. Wang
      Pages 253-274
  4. Regulatory Considerations for Nanomaterial Drug Products

    1. Front Matter
      Pages 275-275
    2. Mamta Kapoor, Kathryn Hughes, Katherine M. Tyner
      Pages 277-299
  5. Cancer Nanotheranostics

    1. Front Matter
      Pages 317-317
    2. James Grant, Mana Naeim, Youngshin Lee, Darron Miya, Theodore Kee, Dean Ho
      Pages 319-344
    3. Camila Gadens Zamboni, Keyvan Farahani, Jordan J. Green
      Pages 345-393
    4. Tianxin Miao, Rachael A. Oldinski, Gang Liu, Xiaoyuan Chen
      Pages 395-428
    5. Abdul K. Parchur, Jaidip M. Jagtap, Gayatri Sharma, Venkateswara Gogineni, Sarah B. White, Amit Joshi
      Pages 429-460
    6. Janel L. Kydd, Praveena Velpurisiva, Stephanie A. Morris, Prakash Rai
      Pages 461-470
  6. Back Matter
    Pages 471-480

About this book

Introduction

This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field.

Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area.

This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

  • Provides a comprehensive review of cancer nanotheranostics
  • Represents the first book-length treatment of the topic
  • Presents a full picture of the field, from basic research through clinical implementation
  • Features evidence-based chapters with excellent illustrations and images to guide and assist the reader

Keywords

Cancer Diagnostics Cancer Nanotechnology Cancer Nanotechnology Case Study Drug Delivery Cancer Drug Delivery Nano Multifunctional Nanoparticles Nanotheranostics Cancer Regulatory Considerations Nanotherapeutics Theranostics Book

Editors and affiliations

  • Prakash Rai
    • 1
  • Stephanie A. Morris
    • 2
  1. 1.Department of Chemical EngineeringUniversity of Massachusetts LowellLowellUSA
  2. 2.National Cancer Institute, NIH Nanodelivery Systems and Devices Branch Cancer Imaging Program, Division of Cancer Treatment and DiagnosisRockvilleUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-030-01775-0
  • Copyright Information This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2019
  • Publisher Name Springer, Cham
  • eBook Packages Engineering
  • Print ISBN 978-3-030-01773-6
  • Online ISBN 978-3-030-01775-0
  • Series Print ISSN 2364-1118
  • Series Online ISSN 2364-1126
  • Buy this book on publisher's site