© 2019

Corneal Regeneration

Therapy and Surgery

  • Jorge L. Alió
  • Jorge L.  Alió del Barrio
  • Francisco Arnalich-Montiel
  • Updates the practical surgeon on the possibilities of using these new methods of corneal regeneration in clinical practice

  • Promotes the development of new surgical approaches for corneal surgery

  • Written and edited by leading experts in the field

  • Discusses the concept of regenerative surgery and future issues related to corneal regenerative surgery and treatment


Part of the Essentials in Ophthalmology book series (ESSENTIALS)

Table of contents

  1. Front Matter
    Pages i-xxv
  2. Corneal Regeneration: The Concept, the Facts, the Potential

    1. Front Matter
      Pages 1-1
    2. Miguel Gonzalez-Andrades, Pablo Argüeso, Ilene Gipson
      Pages 3-12
    3. Veronica Vargas, Francisco Arnalich-Montiel, Jorge L. Alió del Barrio
      Pages 13-22
    4. Mohammad Mirazul Islam, Roholah Sharifi, Miguel Gonzalez-Andrades
      Pages 23-37
  3. The Stem Cell

    1. Front Matter
      Pages 39-39
    2. Natalia Escacena-Acosta, Javier Lopez-Beas, Christian Claude Lachaud, Mehrdad Vakilian, Juan Rigoberto Tejedo, Vivian Capilla-González et al.
      Pages 41-55
    3. Christian Claude Lachaud, Abdelkrim Hmadcha, Bernat Soria
      Pages 57-75
    4. Gustavo S. Figueiredo, Hardeep Singh Mudhar, Majlinda Lako, Francisco C. Figueiredo
      Pages 77-97
    5. Olena Al-Shymali, Jorge L. Alió del Barrio, James L. Funderburgh
      Pages 99-108
    6. Stephen Wahlig, Matthew Lovatt, Gary Swee-Lim Peh, Jodhbir S. Mehta
      Pages 109-122
    7. Christian Claude Lachaud, Abdelkrim Hmadcha, Bernat Soria
      Pages 123-144
    8. Trevor Sherwin, Carol Ann Greene, Colin R. Green, Kushant R. Kapadia
      Pages 145-154
    9. Yuzuru Sasamoto, Yoshinori Oie, Kohji Nishida
      Pages 155-172
  4. Regenerative Surgery and Therapy of the Ocular Surface Epithelium

    1. Front Matter
      Pages 173-173
    2. Harminder Singh Dua, Dalia G. Said
      Pages 175-190
    3. Rafael I. Barraquer, Juan Alvarez de Toledo
      Pages 191-211
    4. Nandini Venkateswaran, Guillermo Amescua
      Pages 213-219
    5. Roberto Fernández Buenaga, Sajjad Ahmad
      Pages 225-230

About this book


This text provides expert instruction on the varying surgical techniques currently employed for the regeneration of the ocular surface. Corneal Regeneration: Therapy and Surgery begins with a thorough discussion of current research based on data obtained in clinical human studies, and discusses the potential clinical implications for this promising new stage of eye surgery. Sections devoted to the stem cell, regenerative surgery and therapy of the ocular surface epithelium, corneal stroma, and corneal endothelium follow, each section comprehensively covering  applied anatomy, current therapy and regenerative techniques, with a look to future directions of the field including eventual cell therapy.


Corneal Regeneration: Therapy and Surgery is the first book of its kind, systematically covering the developments the medical community has achieved in corneal regeneration from all angles. Written and edited by leading experts in the field, researchers and ophthalmologists alike will find this to be a unique source of information on corneal regeneration, as well as a thoughtful reflection on potential applications of regenerative surgery in ophthalmology as a whole.


cornea corneal surgery corneal regeneration corneal blindness corneal therapy

Editors and affiliations

  • Jorge L. Alió
    • 1
  • Jorge L.  Alió del Barrio
    • 2
  • Francisco Arnalich-Montiel
    • 3
  1. 1.Miguel Hernández University AlicanteSpain
  2. 2.Vissum-Instituto Oftalmologico de AlicaUniversity Miguel HernandezAlicanteSpain
  3. 3.Vissum CorporationMadridSpain

About the editors

Prof. Dr Jorge Alió has been Professor and Chairman of Ophthalmology since 1987, first at the University of Alicante and since 2002 at the University Miguel Hernandez de Elche, also in Alicante, Spain. Dr. Alió has been deeply involved since the beginning of his professional career in Academic and Research activities in combination with an intense clinical and surgical practice. His main dedication has been to Cataract, Cornea and Refractive Surgery, even though within the broad basis of his medical education he has been involved in other areas such as Ocular Inflammation (uveitis), Vitreoretinal diseases and Strabismus surgery.  The activities of Dr. Alió are currently mainly oriented on an international basis and he has contributed to the organization, funding and dissemination of different international and Spanish scientific societies. He has collaborated in the organization of many international and Spanish symposiums and congresses, such as the International Ocular Inflammation Society ( IOIS ) the European Society of Cataract and Refractive Surgery ( ESCRS ), The American Academy of Ophthalmology (AAO) the International Society of Refractive Surgery ( ISRS) and the World Ophthalmology Congress ( WOC ) among many others. He has been the author or co-author of 440 peer review papers published in prestigious international scientific journals, 241 book chapters, 78 books (as editor or co-editor), over 200 collaborations in ophthalmic scientific journals and over 1800 presentations and invited lectures in international meetings. 

Bibliographic information

  • Book Title Corneal Regeneration
  • Book Subtitle Therapy and Surgery
  • Editors Jorge L. Alió
    Jorge L. Alió del Barrio
    Francisco Arnalich-Montiel
  • Series Title Essentials in Ophthalmology
  • Series Abbreviated Title Essentials in Ophthalmology
  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-3-030-01303-5
  • eBook ISBN 978-3-030-01304-2
  • Series ISSN 1612-3212
  • Series E-ISSN 2196-890X
  • Edition Number 1
  • Number of Pages XXV, 507
  • Number of Illustrations 60 b/w illustrations, 150 illustrations in colour
  • Topics Ophthalmology
  • Buy this book on publisher's site