Medical Imaging in Clinical Trials

  • Colin G. Miller
  • Joel Krasnow
  • Lawrence H. Schwartz

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Overview and Trial Management

    1. Front Matter
      Pages 1-1
    2. Harris A. Ahmad, Hui Jing Yu, Colin G. Miller
      Pages 3-26
    3. Derek Pearson
      Pages 47-63
    4. Andrea M. Perrone, Jennifer A. Villetard, Colin G. Miller
      Pages 65-82
    5. Joel Krasnow
      Pages 99-133
    6. Eric S. Forsthoffer, Joel Krasnow
      Pages 135-151
  3. Therapeutic Specifics of Medical Imaging

    1. Front Matter
      Pages 153-153
    2. Binsheng Zhao, Lawrence H. Schwartz
      Pages 155-171
    3. George P. Heyrich, Joel Krasnow
      Pages 173-195
    4. Sumit N. Niogi, Apostolos J. Tsiouris
      Pages 197-235
    5. Colin G. Miller, Hui Jing Yu, Cornelis van Kuijk
      Pages 237-251
    6. John A. Shepherd
      Pages 253-275
    7. Amit Mehndiratta, Prabu Anandaraj, Christian M. Zechmann, Frederik L. Giesel
      Pages 293-325
    8. Hendrik von Tengg-Kobligk, Amit Mehndiratta, Frederik L. Giesel
      Pages 327-357
  4. The Future of Imaging in Clinical Trials

    1. Front Matter
      Pages 359-359

About this book

Introduction

Medical Imaging in Clinical Trials is a key text in understanding the methodology and the metrics that are required in the field of medical imaging. As the pharmaceutical, biotech and medical device industries continue to identify ways to improve and speed up product development, medical imaging plays a more significant role.

Medical Imaging in Clinical Trials aims to educate and provide a hands-on text for those involved in clinical trials and either new to medical imaging and having to assimilate it into clinical trials or requiring to understand the key differences between clinical trial imaging and “routine” clinical imaging.  It is targeted to those professionals involved in clinical trials at the clinical research site, pharmaceutical and medical device industries, and regulators.  This is not the “how to image” book written for the radiologist or Radiological Technologist, but covers the critical aspects of clinical trial methodology that are important for these individuals to understand. This book addresses the ethics and radiation dosages of the different modalities, the end points commonly used for the different trial phases, the acquisition and analysis techniques, as well as the logistics management of medical imaging and the role of the central imaging lab or imaging core lab (ICL) which is now the standard requirement for clinical trials.  Furthermore this text delves into the details of the major therapeutic areas where medical imaging plays a primary or secondary efficacy or safety end point.

Editors and affiliations

  • Colin G. Miller
    • 1
  • Joel Krasnow
    • 2
  • Lawrence H. Schwartz
    • 3
  1. 1.Medical AffairsBioClinica Inc.NewtownUSA
  2. 2.Department of Strategy and Regulatory AffairsTherapeuticsMDBoca RatonUSA
  3. 3.Dept. of RadiologyColumbia University Medical CenterNew YorkUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-84882-710-3
  • Copyright Information Springer-Verlag London 2014
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-84882-709-7
  • Online ISBN 978-1-84882-710-3
  • About this book